Histone H3 Antibody, CT, pan, clone A3S, rabbit monoclonal | EMD Millipore 04-928 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3 Antibody, CT, pan, clone A3S, rabbit monoclonal

catalog :

04-928

quantity :

100 μL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

A3S

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 10c	Achuthan A, Cook A, Lee M, Saleh R, Khiew H, Chang M, et al. Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation. J Clin Invest. 2016;126:3453-66 pubmed publisher
chromatin immunoprecipitation; mouse; fig 5	Zhang H, Hu H, Greeley N, Jin J, Matthews A, Ohashi E, et al. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun. 2014;5:5798 pubmed publisher
chromatin immunoprecipitation; mouse	Jefferson W, Chevalier D, Phelps J, Cantor A, Padilla Banks E, Newbold R, et al. Persistently altered epigenetic marks in the mouse uterus after neonatal estrogen exposure. Mol Endocrinol. 2013;27:1666-77 pubmed publisher
	Dion C, Roche S, Laberthonnière C, Broucqsault N, Mariot V, Xue S, et al. SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite. Nucleic Acids Res. 2019;47:2822-2839 pubmed publisher
	Jonsson M, Ragnum H, Julin C, Yeramian A, Clancy T, Frikstad K, et al. Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition. Br J Cancer. 2016;115:929-939 pubmed publisher
	Ene C, Edwards L, Riddick G, Baysan M, Woolard K, Kotliarova S, et al. Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization. PLoS ONE. 2012;7:e51407 pubmed publisher

product information

Catalog Number :

04-928

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3 Antibody, CT, pan, clone A3S, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

Histone H3

Clone :

A3S

Conjugate :

Culture Supernatant

Isotype :

IgG

Product Description :

Anti-Histone H3 Antibody, CT, pan, clone A3S, rabbit monoclonal

Cross Reactivity :

Chicken;Human;Mouse;Rat;Yeast ( S. cerevisiae )

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3;Histone H3

Immunogen :

KLH-conjugated, synthetic peptide corresponding to the C-terminus of human Histone H3

Specificity :

Recognizes Histone H3.

Package Size :

100 μL

Uses :

Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.