phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal

catalog :

04-857

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

2N8

reactivity :

mouse

application :

western blot

product information

Catalog Number :

04-857

Subcategory :

Cell Signaling

Product Name :

Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P12931

Host Name :

Rabbit

Antigen :

phospho-Src family (Tyr416)

Clone :

2N8

Conjugate :

Culture Supernatant

Isotype :

IgG

Product Description :

Anti-phospho-Src family (Tyr416) Antibody, clone 2N8, rabbit monoclonal

Cross Reactivity :

Vertebrates;Mouse

Background :

Src (also known as pp60src) is a non receptor Tyrosine Kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. There are two critical phosphorylation sites of tyrosine on Src, tyrosine 418 and tyrosine 529 (referring to human Src sequence). The tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418. This region of Src is also highly conserved in all of the related Src-family kinases, and thus prior immunoprecipitation may be required to identify which Src family member is being activated.

ALT Names :

KAT13A

Immunogen :

KLH-conjugated, synthetic peptide containing the sequence . NE[pY]TA…, where pY corresponds to phosphotyrosine at position 416 of c-Src

Specificity :

phospho-c-Src (Tyr416)

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.