This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
GluR1 Antibody, clone C3T, rabbit monoclonal
catalog :
04-855
quantity :
100 μL
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C3T
reactivity :
human, mouse, rat, chimpanzee
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 4d
Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, et al. Sez6l2 regulates phosphorylation of ADD and neuritogenesis. Biochem Biophys Res Commun. 2017;494:234-241 pubmed publisher
  • western blot; mouse; 1:500; fig s3
Bosch C, Muhaisen A, Pujadas L, Soriano E, MARTINEZ A. Reelin Exerts Structural, Biochemical and Transcriptional Regulation Over Presynaptic and Postsynaptic Elements in the Adult Hippocampus. Front Cell Neurosci. 2016;10:138 pubmed publisher
  • western blot; mouse; 1:500; fig s2
Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 3a
Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, et al. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons. J Physiol. 2015;593:4373-86 pubmed publisher
  • western blot; mouse; fig 7
Lo S, Wang Y, Weber M, Larson J, Scearce Levie K, Sheng M. Caspase-3 deficiency results in disrupted synaptic homeostasis and impaired attention control. J Neurosci. 2015;35:2118-32 pubmed publisher
  • western blot; rat; 1:1000
Ledonne A, Nobili A, Latagliata E, Cavallucci V, Guatteo E, Puglisi Allegra S, et al. Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. Mol Psychiatry. 2015;20:959-73 pubmed publisher
  • western blot; mouse
  • immunocytochemistry; human
Nagakura I, Van Wart A, Petravicz J, Tropea D, Sur M. STAT1 regulates the homeostatic component of visual cortical plasticity via an AMPA receptor-mediated mechanism. J Neurosci. 2014;34:10256-63 pubmed publisher
Crisp S, Dixon C, Jacobson L, Chabrol E, Irani S, Leite M, et al. Glycine receptor autoantibodies disrupt inhibitory neurotransmission. Brain. 2019;142:3398-3410 pubmed publisher
Wigerblad G, Huie J, Yin H, Leinders M, Pritchard R, Koehrn F, et al. Inflammation-induced GluA1 trafficking and membrane insertion of Ca2+ permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A. Exp Neurol. 2017;293:144-158 pubmed publisher
Tada H, Miyazaki T, Takemoto K, Takase K, Jitsuki S, Nakajima W, et al. Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex. Proc Natl Acad Sci U S A. 2016;113:E7097-E7105 pubmed publisher
Jitsuki S, Nakajima W, Takemoto K, Sano A, Tada H, Takahashi Jitsuki A, et al. Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery. Cereb Cortex. 2016;26:427-439 pubmed publisher
Tada H, Koide M, Ara W, Shibata Y, Funabashi T, Suyama K, et al. Estrous Cycle-Dependent Phasic Changes in the Stoichiometry of Hippocampal Synaptic AMPA Receptors in Rats. PLoS ONE. 2015;10:e0131359 pubmed publisher
Wu Y, Wang X, Tan L, Liu D, Liu X, Wang Q, et al. Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3? and preservation of postsynaptic components. J Alzheimers Dis. 2013;37:515-27 pubmed publisher
Cavallucci V, Berretta N, Nobili A, Nistico R, Mercuri N, D Amelio M. Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease. Neuromolecular Med. 2013;15:541-8 pubmed publisher
Middei S, Houeland G, Cavallucci V, Ammassari Teule M, D Amelio M, Marie H. CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit. Hippocampus. 2013;23:488-99 pubmed publisher
Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb S, Lanfranco M, et al. Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior. J Neurosci. 2012;32:15124-32 pubmed publisher
Bian C, Zhu K, Yang L, Lin S, Li S, Su B, et al. Gonadectomy differentially regulates steroid receptor coactivator-1 and synaptic proteins in the hippocampus of adult female and male C57BL/6 mice. Synapse. 2012;66:849-57 pubmed publisher
Bian C, Zhu K, Guo Q, Xiong Y, Cai W, Zhang J. Sex differences and synchronous development of steroid receptor coactivator-1 and synaptic proteins in the hippocampus of postnatal female and male C57BL/6 mice. Steroids. 2012;77:149-56 pubmed publisher
Incontro S, Ramírez Franco J, Sánchez Prieto J, Torres M. Membrane depolarization regulates AMPA receptor subunit expression in cerebellar granule cells in culture. Biochim Biophys Acta. 2011;1813:14-26 pubmed publisher
product information
Catalog Number :
04-855
Subcategory :
Neuroscience
Product Name :
Anti-GluR1 Antibody, clone C3T, rabbit monoclonal
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P42261
Host Name :
Rabbit
Antigen :
GluR1
Clone :
C3T
Conjugate :
Culture Supernatant
Isotype :
IgG
Product Description :
Anti-GluR1 Antibody, clone C3T, rabbit monoclonal
Cross Reactivity :
Human;Mouse;Rat;Chimpanzee
Background :
L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors that have been divided into 3 groups. Group I includes GRM1 and these receptors have been shown to activate phospholipase C. GRM1 expression has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain and eye libraries.
Immunogen :
KLH-conjugated, synthetic peptide corresponding to amino acids 858-868 (. TLPRNSGAGAS. ) of human GluR1 (amino acids 840-850 of mature human GluR1)
Specificity :
Recognizes GluR1, Mr 106 kDa.
Package Size :
100 μL
Uses :
Immunohistochemistry;Immunoprecipitation;Western Blotting
Storage :
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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