phospho-PPARγ (Ser82) Antibody, clone AW504, rabbit monoclonal | EMD Millipore 04-816 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-PPARγ (Ser82) Antibody, clone AW504, rabbit monoclonal

catalog :

04-816

quantity :

100 μl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

AW504

reactivity :

human, mouse

application :

western blot

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 5c	Friedrich T, Söhn M, Gutting T, Janssen K, Behrens H, Rocken C, et al. Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer. EBioMedicine. 2016;8:159-172 pubmed publisher
western blot; mouse; fig 2	Banks A, McAllister F, Camporez J, Zushin P, Jurczak M, Laznik Bogoslavski D, et al. An ERK/Cdk5 axis controls the diabetogenic actions of PPARÎ³. Nature. 2015;517:391-5 pubmed publisher
	Davoodi Semiromi A, Hassanzadeh A, Wasserfall C, Droney A, Atkinson M. Tyrphostin AG490 agent modestly but significantly prevents onset of type 1 in NOD mouse; implication of immunologic and metabolic effects of a Jak-Stat pathway inhibitor. J Clin Immunol. 2012;32:1038-47 pubmed publisher
	Burgermeister E, Friedrich T, Hitkova I, Regel I, Einwächter H, Zimmermann W, et al. The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor ? through spatial relocalization at helix 7 of its ligand-binding domain. Mol Cell Biol. 2011;31:3497-510 pubmed publisher

product information

Catalog Number :

04-816

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-PPARγ (Ser82) Antibody, clone AW504, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P37231

Host Name :

Rabbit

Antigen :

phospho-PPARγ (Ser82)

Clone :

AW504

Isotype :

IgG

Product Description :

Anti-phospho-PPARγ (Ser82) Antibody, clone AW504, rabbit monoclonal

Cross Reactivity :

Human;Mouse;Rat

Background :

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: ,  and . PPAR stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).

ALT Names :

Nuclear receptor subfamily 1 group C member 3;PPAR gamma;peroxisome proliferative activated receptor gamma;peroxisome proliferator-activated receptor gamma;peroxisome proliferator-activated receptor gamma 1

Immunogen :

KLH-conjugated, synthetic peptide containing the sequence PApSPP in which pS corresponds to phosphoserine at residue 82 of human PPARγ.

Specificity :

PPARγ phosphorylated at Ser82, Mr 55 & 60 kDa.

Package Size :

100 μl

Uses :

Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.