Cytokeratin 18 Antibody, rabbit monoclonal, clone E431-1 | EMD Millipore 04-586 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cytokeratin 18 Antibody, rabbit monoclonal, clone E431-1

catalog :

04-586

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E431-1

The same clone is also sold as:

Invitrogen: MA5-14479
Abcam: ab32118
LifeSpan Biosciences: LS-C88820

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:5000; fig 1	Okinami T, Imamura M, Nishikawa N, Negoro H, Sugino Y, Yoshimura K, et al. Altered detrusor gap junction communications induce storage symptoms in bladder inflammation: a mouse cyclophosphamide-induced model of cystitis. PLoS ONE. 2014;9:e104216 pubmed publisher
	Ng G, Yeh L, Zhang Y, Liu H, Feng G, Kao W, et al. Role of SH2-containing tyrosine phosphatase Shp2 in mouse corneal epithelial stratification. Invest Ophthalmol Vis Sci. 2013;54:7933-42 pubmed publisher
	Makarem M, Kannan N, Nguyen L, Knapp D, Balani S, Prater M, et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 2013;11:e1001630 pubmed publisher

product information

Catalog Number :

04-586

Subcategory :

Cell Structure

Product Name :

Anti-Cytokeratin 18 Antibody, rabbit monoclonal, clone E431-1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05783

Host Name :

Rabbit

Antigen :

Cytokeratin 18

Clone :

E431-1

Conjugate :

Purified

Product Description :

Anti-Cytokeratin 18 Antibody, rabbit monoclonal, clone E431-1

Cross Reactivity :

Human;Mouse;Rat

Background :

Keratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (1-3). Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells, forming alpha-helical coiled-coil dimers which associate laterally and end-to-end to form 10-nm diameter filaments (4).

Immunogen :

A synthetic peptide corresponding to residues of human Cytokeratin 18.

Specificity :

Recognizes Human, Mouse, Rat Cytokeratin 18.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry (Paraffin);Flow Cytometry

Storage :

Store at -20 °C. Stable for 12 months from date of receipt.