This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Smac/DIABLO Antibody, rabbit monoclonal, clone Y12
catalog :
04-578
quantity :
100 µL
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
Y12

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
Catalog Number :
04-578
Subcategory :
Apoptosis & Cancer
Product Name :
Anti-Smac/DIABLO Antibody, rabbit monoclonal, clone Y12
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
Q9NR28
Host Name :
Rabbit
Antigen :
Smac/DIABLO
Clone :
Y12
Conjugate :
Purified
Product Description :
Anti-Smac/DIABLO Antibody, rabbit monoclonal, clone Y12
Cross Reactivity :
Human;Rat
Background :
Smac/DIABLO (Second Mitochondria-derived Activator of Caspases/Direct IAP Binding Protein with Low PI) is localized to the mitochondria and involved in activating programmed cell death, or apoptosis (1). In response to apoptotic stimuli, Smac/DIABLO is released from the mitochondria and binds anti-apoptotic IAP proteins, supressing their inhibitory activity and promoting caspase activation (1,2). This interaction involves primarily the amino-terminal residues of Smac/DIABLO with the BIR3 region of the IAP protein (3,4).
ALT Names :
Second Mitochondria-derived Activator of Caspases/Direct IAP Binding Protein with Low PI
Immunogen :
A synthetic peptide corresponding to C-terminal residues human Smac/DIABLO.
Specificity :
Recognizes Human, Rat Smac/Diablo.
Package Size :
100 µL
Uses :
Flow Cytometry;Immunoprecipitation;Western Blotting;Immunocytochemistry;Immunohistochemistry (Paraffin)
Storage :
Store at -20 °C. Stable for 12 months from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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