PARP-1 (Cleaved p25) Antibody, rabbit monoclonal | EMD Millipore 04-576 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PARP-1 (Cleaved p25) Antibody, rabbit monoclonal

catalog :

04-576

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E51

The same clone is also sold as:

Abcam: ab32064

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

product information

Catalog Number :

04-576

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-PARP-1 (Cleaved p25) Antibody, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09874

Host Name :

Rabbit

Antigen :

PARP-1 (Cleaved p25)

Clone :

E51

Conjugate :

Purified

Product Description :

Anti-PARP-1 (Cleaved p25) Antibody, rabbit monoclonal

Cross Reactivity :

Human;Mouse

Background :

Poly (ADP-ribose) polymerase (PARP) is zinc-dependent DNA binding protein that recognizes DNA strand breaks and is presumed to play a role in DNA repair (1). As a marker for apoptosis, PARP is cleaved in vitro by many caspases, and in vivo by Caspase-3 (2,3). Existing as a 116 kDa nuclear protein, PARP is cleaved between amino acids Asp214 and Gly215 to yield two fragments of 29 kDa (C-terminal catalytic domain) and 85 kDa (N-terminal DNA-binding domain) (2,4).

ALT Names :

poly (ADP-ribose) polymerase-1;ARTD1

Immunogen :

A synthetic peptide corresponding to residues before the cleavage site of human PARP-1. The antibody only recognize p25 cleaved-form of PARP-1.

Specificity :

Recognizes Human, Mouse PARP-1 (Cleaved p25).

Package Size :

100 µL

Uses :

Western Blotting;Flow Cytometry;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry (Paraffin)

Storage :

Store at -20 °C. Stable for 12 months from date of receipt.