RhoG Antibody, clone 1F3 B3 E5 | EMD Millipore 04-486 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RhoG Antibody, clone 1F3 B3 E5

catalog :

04-486

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F3 B3 E5

The same clone is also sold as:

Santa Cruz Biotechnology: sc-80015
BioLegend: 814701

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 7a flow cytometry; rat; loading ...; fig 4b immunohistochemistry; rat; loading ...; fig 1b western blot; rat; loading ...; fig 1a	Ubba V, Soni U, Chadchan S, Maurya V, Kumar V, Maurya R, et al. RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model. Reprod Sci. 2017;24:738-752 pubmed publisher
	Redka D, Gutschow M, Grinstein S, Canton J. Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. Mol Biol Cell. 2018;29:53-65 pubmed publisher
	Moshfegh Y, Bravo Cordero J, Miskolci V, Condeelis J, Hodgson L. A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly. Nat Cell Biol. 2014;16:574-86 pubmed publisher

product information

Catalog Number :

04-486

Subcategory :

Cell Signaling

Product Name :

Anti-RhoG Antibody, clone 1F3 B3 E5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84095

Host Name :

Mouse

Antigen :

RhoG

Clone :

clone 1F3 B3 E5

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-RhoG Antibody, clone 1F3 B3 E5

Cross Reactivity :

Human;Mouse;Rat

Background :

RhoG (ARGH) is a member of the Ras super-family of small G-proteins and a member of the Rac subfamily of Rho Family of GTPases. RhoG is a small G-protein (GTPase) who is activated by a GEF (guanine nucleotide exchange factor). The GEF displaces GDP from the binding site of RhoG and allows GTP to bind in it place rendering the protein active. This active RhoG binds downstream effector molecules that include ELMO and DOCK180. RhoG then cleaves GTP to GDP making it inactive. RhoG is believed to be crucial for integrin-mediated Rac activation and cell spreading. RhoG is believed to be active upstream of Rac and work independently of Rac.

ALT Names :

ARHG;RHOG ras homolog gene family, member G (rho G) ;MGC125835; MGC125836

Immunogen :

KLH synthetic peptide encompassing amino acids CQQDGVKEVFAEAVRAVLNPT (RhoG 160-180)

Specificity :

Recognizes RhoG

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at 2-8°C.