RSK1 Antibody, clone E4,, rabbit monoclonal | EMD Millipore 04-417 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RSK1 Antibody, clone E4,, rabbit monoclonal

catalog :

04-417

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E4

The same clone is also sold as:

Abcam: ab32114

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

04-417

Subcategory :

Cell Signaling

Product Name :

Anti-RSK1 Antibody, clone E4,, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q15418

Host Name :

Rabbit

Antigen :

RSK1

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-RSK1 Antibody, clone E4,, rabbit monoclonal

Cross Reactivity :

Human;Mouse;Rat

Background :

RSK 1 (p90-RSK 1) is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes RSK 1, RSK 2 and RSK 3. These are broadly expressed serine/threonine protein kinases (1) activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2 (2). p90-RSK 1 is activated by MAPK in vitro and in vivo via phosphorylation (3). Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB (2,4).

ALT Names :

ribosomal protein S6 kinase, 90kDa, polypeptide 1;Ribosomal S6 kinase 1;90 kDa ribosomal protein S6 kinase 1;MAP kinase-activated protein kinase 1a;MAPK-activated protein kinase 1a;MAPKAP kinase 1a;ribosomal protein S6 kinase, 90kD, polypeptide 1;dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1);ribosomal protein S6 kinase alpha 1;ribosomal protein S6 kinase alpha-1

Immunogen :

Synthetic peptide corresponding to the N-terminus of human RSK1.

Specificity :

This antibody recognizes the N-terminus of RSK1.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation;Flow Cytometry;Immunohistochemistry

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.