PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal | EMD Millipore 04-397 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal

catalog :

04-397

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

Y92

The same clone is also sold as:

Abcam: ab32570, ab206872

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100	Hum S, Rymer C, Schaefer C, Bushnell D, Sims Lucas S. Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning. PLoS ONE. 2014;9:e88400 pubmed publisher
	Xie T, Liang J, Liu N, Huan C, Zhang Y, Liu W, et al. Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. J Clin Invest. 2016;126:3063-79 pubmed publisher

product information

Catalog Number :

04-397

Subcategory :

Cell Signaling

Product Name :

Anti-PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09619

Host Name :

Rabbit

Antigen :

PDGF Receptor Beta (CT)

Clone :

Y92

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-PDGF Receptor Beta (CT) Antibody, clone Y92, rabbit monoclonal

Cross Reactivity :

Human;Mouse;Rat

Background :

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-Alpha and PDGF receptor-Beta. PDGF receptor-Beta can only bind two specific PDGF isoforms, PDGF-Beta and PDGFDelta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

ALT Names :

platelet-derived growth factor receptor, beta polypeptide;CD140 antigen-like family member B;beta-type platelet-derived growth factor receptor;PDGF-R-beta;CD140b antigen

Immunogen :

Synthetic peptide corresponding to the C-terminus of human PDGF Receptor Beta.

Specificity :

This antibody recognizes the C-terminus of PDGF Receptor Beta. The antibody does not cross-react with other CSF-1/PDGF receptor family members.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.