MYPT1/MYPT2 Antibody, clone YE336, rabbit monoclonal | EMD Millipore 04-386 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MYPT1/MYPT2 Antibody, clone YE336, rabbit monoclonal

catalog :

04-386

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

YE336

The same clone is also sold as:

Abcam: ab32519

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

04-386

Subcategory :

Cell Signaling

Product Name :

Anti-MYPT1/MYPT2 Antibody, clone YE336, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O14974

Host Name :

Rabbit

Antigen :

MYPT1/MYPT2

Clone :

YE336

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-MYPT1/MYPT2 Antibody, clone YE336, rabbit monoclonal

Cross Reactivity :

Human;Mouse;Rat

Background :

The major protein phosphatase-1 (PP1) is composed of 3 subunits with apparent molecular mass of 110 -130, 37 and 20 kDa. The 110-130 kDa component acts as a regulatory subunit known as myosin binding (MBS) or myosin phosphatase targeting subunit (MYPT). The N-terminal portion of MYPT binds to both PP1c-delta and phosphorylated myosin, thereby increasing myosin phosphatase activity. Two isoforms of MYPT have been identified (MYPT1 & MYPT2) and share 61% sequence identity. While MYPT1 is widely distributed in human tissues, MYPT2 is mostly detected in brain and heart.

ALT Names :

protein phosphatase 1, regulatory (inhibitor) subunit 12A;Myosin phosphatase-targeting subunit 1;Protein phosphatase myosin-binding subunit;myosin phosphatase, target subunit 1;protein phosphatase 1 regulatory subunit 12A;Myosin phosphatase target subunit 1

Immunogen :

Synthetic peptide corresponding to the C-terminus of human MYPT1/MYPT2.

Specificity :

This antibody recognizes the C-terminus of MYPT1/MYPT2.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation;Flow Cytometry

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.