IRAK-4 (NT) Antibody, clone Y279, rabbit monoclonal | EMD Millipore 04-368 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IRAK-4 (NT) Antibody, clone Y279, rabbit monoclonal

catalog :

04-368

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

Y279

The same clone is also sold as:

Abcam: ab32511

reactivity :

human

application :

western blot, immunocytochemistry

citations: 1

Reference
Yildirim E, Cınar M, Yalcinkaya I, Ekici H, Atmaca N, Güncüm E. Effect of cocoa butter and sunflower oil supplementation on performance, immunoglobulin, and antioxidant vitamin status of rats. Biomed Res Int. 2014;2014:606575 pubmed publisher

product information

Catalog Number :

04-368

Subcategory :

Cell Signaling

Product Name :

Anti-IRAK-4 (NT) Antibody, clone Y279, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9NWZ3

Host Name :

Rabbit

Antigen :

IRAK-4 (NT)

Clone :

Y279

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-IRAK-4 (NT) Antibody, clone Y279, rabbit monoclonal

Cross Reactivity :

Human

Background :

IRAK-4 is a member of the interleukin-1 receptor-associated kinase (IRAK) family. The IRAK family is implicated in the Toll-like receptor (TLR) and Il-1R signaling pathway (1). Upon phosphorylation, IRAK-4 interacts with IRAK-1, MYD88 and TRAF6 to form a complex, and activate NF-kB and MAPK pathways (2-3). IRAK-4 phosphorylates and activates IRAK-1 at thr387 and is also known to interact with IRAK-1 but not with the other IRAK members. Additionally, like IRAK-1, IRAK-4 possesses an auto and crossphosphorylation kinase activity (4).

ALT Names :

interleukin-1 receptor-associated kinase 4;Renal carcinoma antigen NY-REN-64

Immunogen :

Synthetic peptide corresponding to the N-terminus of human IRAK-4.

Specificity :

This antibody recognizes the N-terminus of IRAK-4.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.