phospho-c-Jun (Ser73) Antibody, clone E107, rabbit monoclonal | EMD Millipore 04-213 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-c-Jun (Ser73) Antibody, clone E107, rabbit monoclonal

catalog :

04-213

quantity :

100 μL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E107

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

product information

Catalog Number :

04-213

Subcategory :

Cell Signaling

Product Name :

Anti-phospho-c-Jun (Ser73) Antibody, clone E107, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P05412

Host Name :

Rabbit

Antigen :

phospho-c-Jun (Ser73)

Clone :

E107

Conjugate :

Culture Supernatant

Isotype :

IgG

Product Description :

Anti-phospho-c-Jun (Ser73) Antibody, clone E107, rabbit monoclonal

Cross Reactivity :

Human;Mouse

Background :

Jun is a component of the transcription factor AP-1, and can constitute AP-1 activity either as a homodimer or as a heterodimer with Fos. By contrast with Fos, Jun is expressed constitutively, and can be activated by phosphorylation of serines 63 and/or 73. These sites are targets for the SAPK1/JNK family of protein kinases, and their phosphorylation states can be monitored using antibodies specific for the phospho-epitopes. In addition, Jun is phosphorylated by GSK3 on sites which inhibit Jun activity. Since GSK3 is inactivated by Akt, the Akt pathway results in Jun activation.

ALT Names :

Activator protein 1;Jun activation domain binding protein;Proto-oncogene c-jun;V-jun avian sarcoma virus 17 oncogene homolog ;enhancer-binding protein AP1;jun oncogene;v-jun sarcoma virus 17 oncogene homolog

Immunogen :

KLH conjugated linear peptide corresponding to Phospho c-Jun.

Specificity :

This antibody recognizes phosphorylated c-Jun at and around Ser73.

Package Size :

100 μL

Uses :

Dot Blot;Flow Cytometry;Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.