phospho-ATF-2 (Thr71) Antibody, clone E268, rabbit monoclonal | EMD Millipore 04-199 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-ATF-2 (Thr71) Antibody, clone E268, rabbit monoclonal

catalog :

04-199

quantity :

100 μL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E268

The same clone is also sold as:

Abcam: ab32019

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

04-199

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-ATF-2 (Thr71) Antibody, clone E268, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P15336

Host Name :

Rabbit

Antigen :

phospho-ATF-2 (Thr71)

Clone :

E268

Conjugate :

Ascites

Isotype :

IgG

Product Description :

Anti-phospho-ATF-2 (Thr71) Antibody, clone E268, rabbit monoclonal

Cross Reactivity :

Human

Background :

The ATF/CREB family of DNA binding proteins consists of transcription factors whose activity is regulated by specific signaling pathways, including the stress/cytokine/radiation inducible pathways that function through SAPK1/JNK activation. Two threonine residues at positions 69 and 71 in the N-terminal region of ATF-2 are essential in mediating adenovirus E1A-inducible transcriptional activation. These residues are efficiently phosphorylated in vivo and are excellent substrates for SAPK1/JNK in vitro.

ALT Names :

activating transcription factor 2 ;activating transcription factor 2 splice variant ATF2-var2;cAMP response element-binding protein CRE-BP1;cAMP responsive element binding protein 2;cAMP responsive element binding protein 2, formerly

Immunogen :

Synthetic peptide directed against the region encompassing and including phosphorylated ATF2 (Thr71).

Specificity :

This antibody recognizes phosphorylated residues surrounding Thr71 of human ATF-2.

Package Size :

100 μL

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.