TLS Antibody, clone 1FU-1D2 | EMD Millipore 04-1552 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TLS Antibody, clone 1FU-1D2

catalog :

04-1552

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1FU-1D2

The same clone is also sold as:

Invitrogen: MA3-089

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

04-1552

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-TLS Antibody, clone 1FU-1D2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35637

Host Name :

Mouse

Antigen :

TLS

Conjugate :

Ascites

Isotype :

IgG1κ

Product Description :

Anti-TLS Antibody, clone 1FU-1D2

Cross Reactivity :

Human;Mouse;Rat

Background :

The TLS/FUS protein contains an RNA-recognition motif and is a component of nuclear riboprotein complexes. It resembles a transcription factor in that it binds DNA, contributes a transcriptional activation domain to the FUS-ERG oncoprotein, and interacts with several transcription factors in vitro. It binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. It may play a role in maintenance of genomic integrity.

ALT Names :

75 kDa DNA-pairing protein;FUS-CHOP fusion protein;FUS-CHOP protein fusion;Fusion gene in myxoid liposarcoma;Oncogene FUS;Oncogene TLS;Translocated in liposarcoma protein;fus-like protein;fus/tls-chop oncogene;fusion (involved in t(12;16) in malignant liposarcoma);fusion, derived from t(12;16) malignant liposarcoma;heterogeneous nuclear ribonucleoprotein P2;translocated in liposarcoma

Immunogen :

Linear peptide corresponding to human TLS.

Specificity :

This antibody recognizes TLS.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.