RARα Antibody, clone 9α-9A6 | EMD Millipore 04-1545 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RARα Antibody, clone 9α-9A6

catalog :

04-1545

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9?-9A6

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

04-1545

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-RARα Antibody, clone 9α-9A6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P10276

Host Name :

Mouse

Antigen :

RARα

Conjugate :

Ascites

Isotype :

IgG1κ

Product Description :

Anti-RARα Antibody, clone 9α-9A6

Cross Reactivity :

Human

Background :

Retinoic acid receptor alpha (RARa) is a nuclear receptor encoded by the RARA gene. This gene is sometimes referred to as NR1B1 (nuclear receptor subfamily 1, group B, member 1). RARa is a member of the steroid/thyroid superfamily of nuclear receptor proteins that regulate gene expression by binding to RNA and other elements of DNA response. As implied by its name, this protein is a receptor for retinoic acid, a metabolite of vitamin A. Retinoic acid is necessary for normal organogenesis, but can act as a teratogen when present at high levels during embryonic and fetal development. During fetal and embryonic development retinoic acid regulates transcription through the activation of nuclear receptors, specifically the Retinoic Acid Receptor (RAR). Signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor (RXR), which form RXR/RAR heterodimers. There are three isoforms associated with RAR; RARα, RARβ and RARγ.

ALT Names :

Nuclear receptor subfamily 1 group B member 1;Retinoic acid receptor, alpha polypeptide;nucleophosmin-retinoic acid receptor alpha fusion protein;NPM-RAR long form;retinoic acid receptor, alpha

Immunogen :

Recombinant protein corresponding to human RARα.

Specificity :

This antibody recognizes RARα.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.