CD86 Antibody, clone IT2.2 | EMD Millipore 04-1528 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CD86 Antibody, clone IT2.2

catalog :

04-1528

quantity :

50 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

IT2.2

The same clone is also sold as:

Rockland Immunochemicals: 200-326-N75, 200-308-N75
Invitrogen: 64-0869-41, 51-0869-42, 16-0869-85, 17-0869-41, 46-0869-42, 16-0869-025, 15-0869-42, 25-0869-42, 12-0869-42, 51-0869-41, 46-0869-41, 63-0869-41, 12-0869-41, 56-0869-42, 62-0869-42, 13-0869-82, 16-0869-050, 63-0869-42, 14-0869-82, 64-0869-42, 25-0869-41, 53-0869-42, 17-0869-42, 53-0869-41
LifeSpan Biosciences: LS-C41120
BioLegend: 305421, 305425, 305422, 305415, 305407, 305414, 305406, 305408, 305429, 305419, 305418, 305430, 305412, 305413, 305404, 305417, 305401, 305434, 305440, 305442, 305420, 305432, 305449, 305416, 305443, 305427, 305423, 305402, 305433, 305428, 305450, 305431, 305439, 305441, 305438, 305426, 305435, 305447, 305411, 305405, 305445
BD Biosciences: 555665, 555663, 555664, 555662

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

product information

Catalog Number :

04-1528

Subcategory :

Inflammation & Immunology

Product Name :

Anti-CD86 Antibody, clone IT2.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42081

Host Name :

Mouse

Antigen :

CD86

Clone :

IT2.2

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-CD86 Antibody, clone IT2.2

Cross Reactivity :

Human

Background :

CD86 (T-lymphocyte activation antigen CD86, activation B7-2 antigen or CTLA-4 counter-receptor B7.2) is a molecule expressed on antigen-presenting cells that provide costimulatory signals necessary for T cell activation and survival. CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. Along with CD80, CD86 provides stimuli to prime T cells against antigens presented by antigen-presenting cells. CD86 is expressed on a broad spectrum of leukocytes, including B lymphocytes, T lymphocytes, macrophages, dendritic cells, and Langerhans cells, plus astrocytes. CD86 is expressed at low levels by freshly explanted peripheral B and T cells, and its expression is substantially increased by a variety of T and B cell-specific stimuli with a peak expression after 18-42 hours of culture. CD86 has also been shown to be involved in immunoglobulin class switching and triggering of mouse NK cell-mediated cytotoxicity.

ALT Names :

Activation B7-2 antigen;B-lymphocyte activation antigen B7-2;B7-2 antigen;CD28 antigen ligand 2;CD86 antigen;CD86 antigen (CD28 antigen ligand 2, B7-2 antigen);CD86 molecule;CTLA-4 counter-receptor B7.2

Immunogen :

Human LCL whole cells.

Specificity :

This antibody recognizes CD86.

Package Size :

50 µL

Uses :

Flow Cytometry;Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt