Vitamin D receptor Antibody, clone 9A7 | EMD Millipore 04-1526 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Vitamin D receptor Antibody, clone 9A7

catalog :

04-1526

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

9A7

The same clone is also sold as:

Invitrogen: MA1-710

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Lopes N, Sousa B, Martins D, Gomes M, Vieira D, Veronese L, et al. Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions. BMC Cancer. 2010;10:483 pubmed publisher

product information

Catalog Number :

04-1526

Subcategory :

Cell Signaling

Product Name :

Anti-Vitamin D receptor Antibody, clone 9A7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11473

Host Name :

Rat

Antigen :

Vitamin D receptor

Clone :

9A7

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Vitamin D receptor Antibody, clone 9A7

Cross Reactivity :

Human;Vertebrates

Background :

Vitamin D receptor (VDR) is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or transrepression of specific gene products. In humans, the vitamin D receptor is encoded by the VDR gene. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows similarity of sequence to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.

ALT Names :

1,25-dihydroxyvitamin D3 receptor ;Nuclear receptor subfamily 1 group I member 1 ;vitamin D (1,25- dihydroxyvitamin D3) receptor ;vitamin D (1,25-dihydroxyvitamin D3) receptor

Immunogen :

Partially purified chicken intestinal vitamin D receptor.

Specificity :

This antibody detects vitamin D receptor.

Package Size :

100 µg

Uses :

Western Blotting;Immunohistochemistry (Paraffin);Immunoprecipitation;Affects Function

Storage :

Stable for 1 year at 2-8ºC from date of receipt.