CTCF Antibody, clone 2.24.3.10.1.4 | EMD Millipore 04-1498 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CTCF Antibody, clone 2.24.3.10.1.4

catalog :

04-1498

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2.24.3.10.1.4

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation

product information

Catalog Number :

04-1498

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-CTCF Antibody, clone 2.24.3.10.1.4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P49711

Host Name :

Mouse

Antigen :

CTCF

Clone :

2.24.3.10.1.4

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-CTCF Antibody, clone 2.24.3.10.1.4

Cross Reactivity :

Human

Background :

CTCF, also known as CCCTC-binding factor, contains 11 zinc finger (ZF) binding domains that allow it to bind different DNA target sequences and proteins. This multifunctional protein can act as a transcriptional activator or repressor. As a transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. CTCF also acts as a transcriptional activator of APP. It is involved in different aspects of gene regulation including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting. Mutations of CTCF in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms tumors, suggesting a role for CTCF may as a tumor suppressor.

ALT Names :

11 zinc finger transcriptional repressor;11-zinc finger protein;CCCTC-binding factor;CCCTC-binding factor (zinc finger protein);CTCFL paralog;transcriptional repressor CTCF

Immunogen :

His-tagged recombinant protein corresponding to human CTCF.

Specificity :

This antibody recognizes CTCF.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunohistochemistry;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt