PABP 1 Antibody, clone 10E10 | EMD Millipore 04-1467 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PABP 1 Antibody, clone 10E10

catalog :

04-1467

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10E10

The same clone is also sold as:

Abnova: MAB2465
LifeSpan Biosciences: LS-C82271, LS-C82229
Invitrogen: MA1-34079
Santa Cruz Biotechnology: sc-32318
ImmuQuest: IQ272, IQ216
Abcam: ab6125

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Reference
Kourtidis A, Necela B, Lin W, Lu R, Feathers R, Asmann Y, et al. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017;216:3073-3085 pubmed publisher
Huichalaf C, Schoser B, Schneider Gold C, Jin B, Sarkar P, Timchenko L. Reduction of the rate of protein translation in patients with myotonic dystrophy 2. J Neurosci. 2009;29:9042-9 pubmed publisher

product information

Catalog Number :

04-1467

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PABP 1 Antibody, clone 10E10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11940

Host Name :

Mouse

Antigen :

PABP 1

Clone :

10E10

Conjugate :

Purified

Product Description :

Anti-PABP 1 Antibody, clone 10E10

Cross Reactivity :

Human

Background :

Poly(A)-binding protein (PABP 1) is an abundant protein that interacts with the 3' poly(A) tail of most eukaryotic mRNAs. In vivo this protein is involved in many aspects of mRNA metabolism, including mRNA stability, translationally coupled mRNA turnover, protein biosynthesis, and ribosome biogenesis. PABP1 shuttles between the cytoplasm and the nucleus and may bind to cytoplasmic RNA sequences other than poly(A). PABP1 accumulates in the nucleus if transcription is inhibited, suggesting that nuclear export is coupled to active transcription.

ALT Names :

PABP 1;Poly(A)-binding protein 1;poly(A) binding protein, cytoplasmic 1;poly(A) binding protein, cytoplasmic 2;poly(A)-binding protein, cytoplasmic 2

Immunogen :

Recombinant protein corresponding to human PABP 1.

Specificity :

This antibody recognizes PABP 1.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt