PRMT5 Antibody, clone 23C7 | EMD Millipore 04-1460 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PRMT5 Antibody, clone 23C7

catalog :

04-1460

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

23C7

The same clone is also sold as:

Santa Cruz Biotechnology: sc-136202

reactivity :

human

application :

western blot

product information

Catalog Number :

04-1460

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PRMT5 Antibody, clone 23C7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O14744

Host Name :

Mouse

Antigen :

PRMT5

Clone :

23C7

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-PRMT5 Antibody, clone 23C7

Cross Reactivity :

Human

Background :

Arginine methylation of proteins is mediated by the Protein-Arginine Methyl Transferase (PRMT) family of enzymes, which are important in signal transduction, transcription, RNA transport, and splicing. PRMTs are divided into two types defined by their activity. Type I PRMTs (including PRMT 1, 3, 4, and 6) are characterized by the formation of asymmetric dimethylated arginine residues. Type II PRMTs, which include only PRMT5, are defined by the formation of symmetric dimethylated arginine residues. Substrates for PRMT5 include myelin basic protein (MBP) and the spliceosomal D1 and D3 proteins. PRMT5 (also known as Skb1Hs/JBP1) exists as homooligomeric complexes, which includes a dimer and tetramer. Homooligomerization of PRMT5 has an important role in its ability to methylate the MBP protein.

ALT Names :

72 kDa ICln-binding protein;HMT1 hnRNP methyltransferase-like 5;Jak-binding protein 1;SKB1 homolog;SKB1 homolog (S. pombe);Shk1 kinase-binding protein 1 homolog;protein arginine methyltransferase 5;skb1 (S. pombe) homolog

Immunogen :

Recombinant protein corresponding to human PRMT5.

Specificity :

This antibody recognizes PRMT5.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt