NOD2 Antibody, clone 2D9 | EMD Millipore 04-145 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

NOD2 Antibody, clone 2D9

catalog :

04-145

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D9

The same clone is also sold as:

Invitrogen: MA1-16611
Abnova: MAB2303
LifeSpan Biosciences: LS-C141157, LS-C141212, LS-C141211, LS-C141210, LS-C2580
Abcam: ab31488
Santa Cruz Biotechnology: sc-56168
Novus Biologicals: NBP2-80883, NB100-524

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:500 western blot; human	Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer T, et al. The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process. J Biol Chem. 2012;287:29213-26 pubmed publisher

product information

Catalog Number :

04-145

Subcategory :

Inflammation & Immunology

Product Name :

Anti-NOD2 Antibody, clone 2D9

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9HC29

Host Name :

Mouse

Antigen :

NOD2

Clone :

2D9

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-NOD2 Antibody, clone 2D9

Cross Reactivity :

Human

Background :

NOD2 (nucleotide-binding oligomerization domain containing 2), also known as the caspase recruitment domain family, member 15 (CARD15), is a member of the NOD-like Receptor (NLR) family of proteins and plays an important role in the immune system. It is an intracellular pattern recognition receptor and is linked to inflammatory diseases such as inflammatory bowel disease/Crohn's Disease and Blau syndrome. NOD2 has two caspase recruitment domains (CARDs) and eleven leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response by recognizing the bacterial molecules. Recently it is has been found to interact with NLRC4 and bind to MAVS in response to ssRNA or viral RNA treatment and activate the IFN response.

ALT Names :

Caspase recruitment domain-containing protein 15;Inflammatory bowel disease protein 1;NLR family, CARD domain containing 2;NOD-like receptor C2;caspase recruitment domain family, member 15;caspase recruitment domain protein 15;nucleotide-binding oligomerization domain 2;nucleotide-binding oligomerization domain containing 2;nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2

Immunogen :

His-tagged recombinant protein corresponding to human NOD2.

Specificity :

This antibody recognizes NOD2.

Package Size :

100 μg

Uses :

Immunohistochemistry;Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt