phospho-Histone H3 (Ser10) Antibody, clone E173, rabbit monoclonal | EMD Millipore 04-1093 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-Histone H3 (Ser10) Antibody, clone E173, rabbit monoclonal

catalog :

04-1093

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E173

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:1600; loading ...; fig 5a	Hennika T, Hu G, Olaciregui N, Barton K, Ehteda A, Chitranjan A, et al. Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models. PLoS ONE. 2017;12:e0169485 pubmed publisher
	Hua K, Nie Y, Hou J, Zheng Z, Hu S. Cardiomyocyte cytokinesis score: a potential method for cardiomyocyte proliferation. Cell Biol Int. 2014;38:1032-40 pubmed publisher
	Haubner B, Adamowicz Brice M, Khadayate S, Tiefenthaler V, Metzler B, Aitman T, et al. Complete cardiac regeneration in a mouse model of myocardial infarction. Aging (Albany NY). 2012;4:966-77 pubmed
	Shan W, Akinfenwa P, Savannah K, Kolomeyevskaya N, Laucirica R, Thomas D, et al. A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma. Clin Cancer Res. 2012;18:3352-65 pubmed publisher

product information

Catalog Number :

04-1093

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-Histone H3 (Ser10) Antibody, clone E173, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84243

Host Name :

Rabbit

Antigen :

phospho-Histone H3 (Ser10)

Clone :

E173

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-phospho-Histone H3 (Ser10) Antibody, clone E173, rabbit monoclonal

Cross Reactivity :

Human;Rat;Mouse

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3S10P;Histone H3 (phospho S10);H3 histone, family 3A

Immunogen :

Phospho-synthetic peptide corresponding to residues surrounding Ser10 of Human Histone H3.

Specificity :

The antibody only detects Histone H3 phosphorylated on Ser10.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry (Paraffin);Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.