Caspase-3 (Pro) Antibody, clone E83-103, rabbit monoclonal | EMD Millipore 04-1088 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Caspase-3 (Pro) Antibody, clone E83-103, rabbit monoclonal

catalog :

04-1088

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E83-103

The same clone is also sold as:

OriGene: TA300422

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

product information

Catalog Number :

04-1088

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Caspase-3 (Pro) Antibody, clone E83-103, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P42574

Host Name :

Rabbit

Antigen :

Caspase-3 (Pro)

Clone :

E83-103

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-Caspase-3 (Pro) Antibody, clone E83-103, rabbit monoclonal

Cross Reactivity :

Human;Mouse

Background :

Caspase-3 (CPP32, Apopain) is the most extensively studied apoptotic protein. Caspase-3 is synthesized as an inactive proenzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kDa) and small (12 kDa) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells such as PARP and DFF.

ALT Names :

Cysteine protease CPP32;PARP cleavage protease ;SREBP cleavage activity 1;Yama protein;caspase 3;caspase 3, apoptosis-related cysteine peptidase ;caspase 3, apoptosis-related cysteine protease

Immunogen :

Synthetic peptide corresponding to residues following Ser29 of human caspase-3 (N-terminus of p17 subunit).

Specificity :

This antibody only detects pro-form (35kD) of caspase-3, and does not recognize any cleaved caspases.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation;Immunohistochemistry (Paraffin);Immunocytochemistry;Flow Cytometry

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.