This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Synaptophysin (CT) Antibody, clone YE269, rabbit monoclonal
catalog :
04-1019
quantity :
100 µL
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
YE269

The same clone is also sold as:
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 8e
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed publisher
  • immunohistochemistry; mouse
Chang W, Chen M, Cheng I. Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease. Sci Rep. 2015;5:15067 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500
Liu S, Zheng S, Dan Q, Liu J, Wang T. Effects of Governor Vessel electroacupuncture on the systematic expressions of NTFs in spinal cord transected rats. Neuropeptides. 2014;48:239-47 pubmed publisher
Huang J, Zhou L, Wang H, Luo J, Zeng L, Xiong K, et al. Distribution of thrombospondins and their neuronal receptor ?2?1 in the rat retina. Exp Eye Res. 2013;111:36-49 pubmed publisher
Leroy K, Ando K, Laporte V, Dedecker R, Suain V, Authelet M, et al. Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice. Am J Pathol. 2012;181:1928-40 pubmed publisher
Bian C, Zhu K, Yang L, Lin S, Li S, Su B, et al. Gonadectomy differentially regulates steroid receptor coactivator-1 and synaptic proteins in the hippocampus of adult female and male C57BL/6 mice. Synapse. 2012;66:849-57 pubmed publisher
Mitani Y, Yarimizu J, Saita K, Uchino H, Akashiba H, Shitaka Y, et al. Differential effects between ?-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice. J Neurosci. 2012;32:2037-50 pubmed publisher
Morel M, Héraud C, Nicaise C, Suain V, Brion J. Levels of kinesin light chain and dynein intermediate chain are reduced in the frontal cortex in Alzheimer's disease: implications for axoplasmic transport. Acta Neuropathol. 2012;123:71-84 pubmed publisher
Bian C, Zhu K, Guo Q, Xiong Y, Cai W, Zhang J. Sex differences and synchronous development of steroid receptor coactivator-1 and synaptic proteins in the hippocampus of postnatal female and male C57BL/6 mice. Steroids. 2012;77:149-56 pubmed publisher
Haider L, Fischer M, Frischer J, Bauer J, Hoftberger R, Botond G, et al. Oxidative damage in multiple sclerosis lesions. Brain. 2011;134:1914-24 pubmed publisher
Bono A, Montironi R, Pannellini T, Sasso F, Mirone V, Musiani P, et al. Effects of castration on the development of prostate adenocarcinoma from its precursor HGPIN and on the occurrence of androgen-independent, poorly differentiated carcinoma in TRAMP mice. Prostate Cancer Prostatic Dis. 2008;11:377-83 pubmed publisher
product information
Catalog Number :
04-1019
Subcategory :
Neuroscience
Product Name :
Anti-Synaptophysin (CT) Antibody, clone YE269, rabbit monoclonal
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P08247
Host Name :
Rabbit
Antigen :
Synaptophysin (CT)
Clone :
YE269
Conjugate :
Unpurified
Isotype :
IgG
Product Description :
Anti-Synaptophysin (CT) Antibody, clone YE269, rabbit monoclonal
Cross Reactivity :
Mouse;Rat;Human;Bovine
Background :
Synaptophysin is a protein of the presynaptic vesicle exocytosis machinery interacting at the vesicle with VAMP/synaptobrevin. Synaptophysin structure consists of a hexameric protein of four transmembrane spans with cytoplasmic amino and carboxyl termini. Although its actual function remains elusive, synaptophysin remains a specific presynaptic marker for all neurons, neuroendocrine cells and neuroderived neoplasms.
ALT Names :
Major synaptic vesicle protein p38
Immunogen :
Synthetic peptide corresponding to residues in C-terminus (cytoplasmic domain) of human Synaptophysin.
Specificity :
This antibody recognizes Synaptophysin at and around the c-terminus.
Package Size :
100 µL
Uses :
Western Blotting;Immunocytochemistry;Immunohistochemistry
Storage :
Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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