phospho-MEK1/2 Ser218/Ser222) Antibody, clone E237, rabbit monoclonal | EMD Millipore 04-1017 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-MEK1/2 Ser218/Ser222) Antibody, clone E237, rabbit monoclonal

catalog :

04-1017

quantity :

100 µL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

E237

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Catalog Number :

04-1017

Subcategory :

Cell Signaling

Product Name :

Anti-phospho-MEK1/2 Ser218/Ser222) Antibody, clone E237, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q02750

Host Name :

Rabbit

Antigen :

phospho-MEK1/2 Ser218/Ser222)

Clone :

E237

Conjugate :

Unpurified

Isotype :

IgG

Product Description :

Anti-phospho-MEK1/2 Ser218/Ser222) Antibody, clone E237, rabbit monoclonal

Cross Reactivity :

Human

Background :

MEK1/2, also known as MAP2K1, are mitogen activated protein kinases and are involved in cell growth and differentiation. MEK is activated by a variety of growth factors and cytokines resulting in phosphorylation at Ser217/218 and Ser221/222. Diseases associated with MEK1/2 is cardio-facio- cutaneous syndrome (CFC), which is an autosomal dominant trait.

ALT Names :

MAP kinase kinase 1;MAPK/ERK kinase 1;MAPKK 1 ;mitogen-activated protein kinase kinase 1;protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1);ERK activator kinase 1

Immunogen :

Phospho-synthetic peptide corresponding to residues surrounding Ser218 and Ser222 of human MEK1/2.

Specificity :

The antibody only detects MEK1/2 phosphorylated on Ser218 and Ser222.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.