RIPAb+™ hnRNPA1 (M9 Region) - RIP Validated Antibody and Primer Set

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RIPAb+™ hnRNPA1 (M9 Region) - RIP Validated Antibody and Primer Set

catalog :

03-181

quantity :

10 assays

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation

product information

Catalog Number :

03-181

Subcategory :

Epigenetics & Nuclear Function

Product Name :

RIPAb+™ hnRNPA1 (M9 Region) - RIP Validated Antibody and Primer Set

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P09651

Host Name :

Mouse

Antigen :

hnRNPA1 (M9 Region)

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

RIPAb+™ hnRNPA1 (M9 Region) - RIP Validated Antibody and Primer Set

Cross Reactivity :

Human

Background :

The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and associate with pre-mRNAs in the nucleus. These complexes are associated with pre-mRNA processing and other aspects of mRNA metabolism and transport. While all hnRNPs are present in the nucleus, data suggests they shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by hnRNP A1 has two repeats of quasi-RRM domains that bind to RNAs. This abundant core protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. The hnRNP A1 protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may have a role in splice site selection.

ALT Names :

Helix-destabilizing protein;Single-strand RNA-binding protein;heterogeneous nuclear ribonucleoprotein A1;heterogeneous nuclear ribonucleoprotein A1B protein;heterogeneous nuclear ribonucleoprotein B2 protein;heterogeneous nuclear ribonucleoprotein core protein A1;hnRNP core protein A1;nuclear ribonucleoprotein particle A1 protein;single-strand DNA-binding protein UP1

Immunogen :

Recombinant protein corresponding to human hnRNP A1.

Specificity :

This antibody recognizes hnRNP A1.

Package Size :

10 assays

Uses :

RNA Binding Protein Immunoprecipitation (RIP);Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.