Synaptic vesicle proteoglycan/Notochord marker | Developmental Studies Hybridoma Bank tor70/Notochord Ab1 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Synaptic vesicle proteoglycan/Notochord marker

catalog :

tor70/Notochord Ab1

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

tor70/Notochord Ab1

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 25

Reference
Buisson N, Sirour C, Moreau N, Denker E, Le Bouffant R, Goullancourt A, et al. An adhesome comprising laminin, dystroglycan and myosin IIA is required during notochord development in Xenopus laevis. Development. 2014;141:4569-79 pubmed publisher
Peyrot S, Wallingford J, Harland R. A revised model of Xenopus dorsal midline development: differential and separable requirements for Notch and Shh signaling. Dev Biol. 2011;352:254-66 pubmed publisher
Krneta Stankic V, Sabillo A, Domingo C. Temporal and spatial patterning of axial myotome fibers in Xenopus laevis. Dev Dyn. 2010;239:1162-77 pubmed publisher
Fukuda M, Takahashi S, Haramoto Y, Onuma Y, Kim Y, Yeo C, et al. Zygotic VegT is required for Xenopus paraxial mesoderm formation and is regulated by Nodal signaling and Eomesodermin. Int J Dev Biol. 2010;54:81-92 pubmed publisher
Chu F, Afonin B, Gustin J, Bost A, Sanchez M, Domingo C. Embryonic cells depleted of beta-catenin remain competent to differentiate into dorsal mesodermal derivatives. Dev Dyn. 2007;236:3007-19 pubmed
Skoglund P, Keller R. Xenopus fibrillin regulates directed convergence and extension. Dev Biol. 2007;301:404-16 pubmed
Patil S, Alexander T, Uzman J, Lou C, Gohil H, Sater A. Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning. Dev Dyn. 2006;235:1895-907 pubmed
Wunderlich K, Gustin J, Domingo C. Muscle specification in the Xenopus laevis gastrula-stage embryo. Dev Dyn. 2005;233:1348-58 pubmed
Fukumoto T, Kema I, Levin M. Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos. Curr Biol. 2005;15:794-803 pubmed
Abe T, Furue M, Kondow A, Matsuzaki K, Asashima M. Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A. Mech Dev. 2005;122:671-80 pubmed
Davidson L, Keller R, DeSimone D. Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis. Gene Expr Patterns. 2004;4:457-66 pubmed
Marsden M, DeSimone D. Integrin-ECM interactions regulate cadherin-dependent cell adhesion and are required for convergent extension in Xenopus. Curr Biol. 2003;13:1182-91 pubmed
Ezin A, Skoglund P, Keller R. The midline (notochord and notoplate) patterns the cell motility underlying convergence and extension of the Xenopus neural plate. Dev Biol. 2003;256:100-14 pubmed
Cheyette B, Waxman J, Miller J, Takemaru K, Sheldahl L, Khlebtsova N, et al. Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation. Dev Cell. 2002;2:449-61 pubmed
Lane M, Keller R. Microtubule disruption reveals that Spemann's organizer is subdivided into two domains by the vegetal alignment zone. Development. 1997;124:895-906 pubmed
Baker J, Harland R. A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 1996;10:1880-9 pubmed
Shih J, Fraser S. Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage. Development. 1996;122:1313-22 pubmed
Saint Jeannet J, Dawid I. Vertical versus planar neural induction in Rana pipiens embryos. Proc Natl Acad Sci U S A. 1994;91:3049-53 pubmed
Taira M, Otani H, Jamrich M, Dawid I. Expression of the LIM class homeobox gene Xlim-1 in pronephros and CNS cell lineages of Xenopus embryos is affected by retinoic acid and exogastrulation. Development. 1994;120:1525-36 pubmed
Kushner P. A library of monoclonal antibodies to Torpedo cholinergic synaptosomes. J Neurochem. 1984;43:775-86 pubmed
Buckley K, Schweitzer E, Miljanich G, Clift O Grady L, Kushner P, Reichardt L, et al. A synaptic vesicle antigen is restricted to the junctional region of the presynaptic plasma membrane. Proc Natl Acad Sci U S A. 1983;80:7342-6 pubmed
Carlson S, Kelly R. A highly antigenic proteoglycan-like component of cholinergic synaptic vesicles. J Biol Chem. 1983;258:11082-91 pubmed
Bjornskov E, Stephenson D, Kushner P. Torpedo monoclonal antibodies react with components of the human peripheral nervous system. Muscle Nerve. 1988;11:10-20 pubmed
Bolce M, Hemmati Brivanlou A, Kushner P, Harland R. Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin. Development. 1992;115:681-8 pubmed
Hemmati Brivanlou A, Wright D, Melton D. Embryonic expression and functional analysis of a Xenopus activin receptor. Dev Dyn. 1992;194:1-11 pubmed

product information

Internal ID :

29609

Name :

tor70/Notochord Ab1

Depositor Name :

Harland, Richard

Depositor Institution :

University of California, Berkeley

Depositor Website :

https://mcb.berkeley.edu/labs/harland/

Date Deposited :

6/20/17

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Synaptic vesicle proteoglycan/Notochord marker

Antigen Species :

Torpedo

Host Species :

mouse

Isotype :

MIgM

Positive Tested Species Reactivity :

Axolotl,Human,Rana Pipiens,Rat,Torpedo,Xenopus,Zebrafish

Initial Publication Pubmed ID :

6379104 1425347

Depositor Notes (Special Instructions) :

This antibody was generated by Pinky Kushner in 1984. This antigen is also known as SV1 and labels a proteoglycan on the luminal face of synaptic vesicles.

Collections :

Human,Neurodevelopment,Xenopus

Search Keywords :

Richard Harland, Synaptic vesicle proteoglycan /Notochord marker, Torpedo, MIgM , Xenopus/Torpedo/Human/Zebrafish/Axolotl/Rat/Rana Pipiens, , , , Monoclonal, Human/Xenopus/Neurodevelopment markers/, Immunoprecipitation/Immunohistochemistry/Immunofluorescence/Western blot/FFPE

Antigen Molecular Weight :

100-200 kDa

Antibody Registry ID :

AB_2722485

Immunogen :

Purified cholinergic synaptosomes from Torpedo electric organ

Clonality :

Monoclonal

Myeloma Strain :

NS1

Epitope Mapped :

Recommended Applications :

FFPE,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunohistochemistry Pubmed IDs :

15817224 15965978 8620858 16680723 11970895 8756346 1384808 21276789 8159704 7914163 9043070 17027959 15886096 20013651 1425347 12654295

Immunofluorescence Pubmed IDs :

3340098 20235228 17907203 25359726 20235228 15183313 12867028

Western Blot Pubmed IDs :

6359167 6193120

Immunoprecipitation Pubmed IDs :

6359167 6193120

FFPE Pubmed IDs :

15817224

Additional Information :

This antibody was generated by Pinky Kushner in 1984 as part of a library of monoclonal antibodies to Torpedo cholinergic synaptosomes. RRID:AB_2722485

Additional Characterization :

http://www.xenbase.org/reagents/antibodyAction.do?method=displayAntibodySummary&antibodyId=14579003

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage