product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Enolase superfamily member 1, Mitochondrial
catalog :
rTSB D3
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
rTSB D3
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 3
Reference
Kuo S, Wang H, Chow K, Chiou S, Chiang S, Lin T, et al. Expression of rTSbeta as a 5-fluorouracil resistance marker in patients with primary breast cancer. Oncol Rep. 2008;19:881-8 pubmed
Liang P, Nair J, Song L, McGuire J, Dolnick B. Comparative genomic analysis reveals a novel mitochondrial isoform of human rTS protein and unusual phylogenetic distribution of the rTS gene. BMC Genomics. 2005;6:125 pubmed
Dolnick R, Wu Q, Angelino N, Stephanie L, Chow K, Sufrin J, et al. Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells. Cancer Res. 2005;65:5917-24 pubmed
product information
Internal ID :
16681
Name :
rTSB D3
Depositor Name :
Dolnik, B.J.
Depositor Institution :
Roswell Park Cancer Institute
Date Deposited :
5/9/11
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
Enolase superfamily member 1, Mitochondrial
Antigen Species :
Human
Host Species :
mouse
Isotype :
MIgG1
Positive Tested Species Reactivity :
Human
Initial Publication Pubmed ID :
15994970
Depositor Notes (Special Instructions) :
This antibody recognizes protein isoforms that are involved in the regulation of thymidylate synthase gene expression.
Collections :
Enzymes,Human
Search Keywords :
Dolnik, B.J., Enolase superfamily member 1, Mitochondrial, Human, MIgG1, Human, ENOSF1, HSRTSBETA, rTS, TYMSAS, , Monoclonal
Antigen Molecular Weight :
49.7 kDa
Gene :
ENOSF1
Alternate Gene Name(s) :
HSRTSBETA, rTS, TYMSAS
Uniprot ID :
Q7L5Y1
Antibody Registry ID :
AB_2617416
Immunogen :
Recombinant Protein
Immunogen Sequence :
Full sequence
Clonality :
Monoclonal
Epitope Mapped :
No
Recommended Applications :
ELISA,Immunofluorescence,Immunohistochemistry,Western Blot
Immunohistochemistry Pubmed IDs :
18357371
Immunofluorescence Pubmed IDs :
18357371
Western Blot Pubmed IDs :
15994970 16162288 18357371
ELISA Pubmed IDs :
18357371
Additional Information :
This antibody detects four bands by western blot: 48 kDa (rTSbeta), 52kDa (rTSgamma), 42kDa (rTSalpha), and66kDa (summoylated rTS beta). RRID:AB_2617416
DSHB Growth Medium :
Iscove's
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US