mineralocorticoid receptor | Developmental Studies Hybridoma Bank rMR365 4D6 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

mineralocorticoid receptor

catalog :

rMR365 4D6

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

rMR365 4D6

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 3

Reference
Jiménez Canino R, Lorenzo Díaz F, Odermatt A, Bailey M, Livingstone D, Jaisser F, et al. 11?-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology. 2017;158:4047-4063 pubmed publisher
Jiménez Canino R, Lorenzo Díaz F, Jaisser F, Farman N, Giraldez T, Alvarez de la Rosa D. Histone Deacetylase 6-Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional Activity. Endocrinology. 2016;157:2515-32 pubmed publisher
Gomez Sanchez C, de Rodriguez A, Romero D, Estess J, Warden M, Gomez Sanchez M, et al. Development of a panel of monoclonal antibodies against the mineralocorticoid receptor. Endocrinology. 2006;147:1343-8 pubmed

product information

Internal ID :

3484

Name :

rMR365 4D6

Depositor Name :

Gomez-Sanchez, C.

Depositor Institution :

G.V. Montgomery VA Medical Center

Date Deposited :

10/2/07

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

mineralocorticoid receptor

Antigen Species :

Rat

Host Species :

mouse

Isotype :

MIgG2a, kappa light chain

Isotype for catalog (legacy) :

IgG2a, kappa light chain

Positive Tested Species Reactivity :

Mouse,Rat

Species Tested (legacy) :

rat, mouse

Initial Publication Pubmed ID :

16293659

Collections :

Cell adhesion,Cell signaling,Nucleus,Transcription factors

Search Keywords :

Gomez-Sanchez, C., mineralocorticoid receptor, Rat, MIgG2a, kappa light chain, Rat/Mouse, Nr3c2, Mlr, MCR, AB_2267538, monoclonal, Cell signaling/Transcription factors/Nucleus, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Predicted: 107 kDa; Apparent: 107 kDa

Gene :

Nr3c2

Alternate Gene Name(s) :

Mlr, MCR

Uniprot ID :

P22199

Antibody Registry ID :

AB_2267538

Synonyms (Alternate Clone Names) :

rMR 365–381 4D6

Immunogen :

THEKGAHDVPFPKTEEV+C (KLH)

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Myeloma Strain :

SP2

Epitope Mapped :

Yes

Epitope Location or Sequence :

N-terminus A/B domain (aa 365-381)

Epitope Map PubMed ID :

16293659

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

16293659

Western Blot Pubmed IDs :

16293659 27100623

Additional Information :

Should recognize all MR isoforms. The sequence of the rMR 365–381 peptide is identical between rat and mouse, but differs in human.

DSHB Growth Medium :

Iscove's

References (legacy) :

Endocrinology 147:1343-1348.

more info or order :

Developmental Studies Hybridoma Bank product webpage