GP dipeptide repeat proteins, poly(GP) | Developmental Studies Hybridoma Bank poly(GP) TALS 828.66 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

GP dipeptide repeat proteins, poly(GP)

catalog :

poly(GP) TALS 828.66

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

poly(GP) TALS 828.66

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

product information

Internal ID :

31320

Name :

poly(GP) TALS 828.66

Depositor Name :

Target ALS Foundation

Depositor Institution :

Target ALS Foundation

Depositor Website :

http://www.targetals.org/

Date Deposited :

5/3/18

Allow Hybridoma Distribution :

Cells Available (legacy) :

Antigen :

GP dipeptide repeat proteins, poly(GP)

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Positive Tested Species Reactivity :

Human

Depositor Notes (Special Instructions) :

This antibody recognizes poly(GP) dipeptide repeat proteins produced from an expanded hexanucleotide (GGGGCC) repeat in the first intron of C9ORF72, the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The expanded GGGGCC repeat undergoes an atypical form of translation - repeat-associated non-ATG (RAN) translation - forming various dipeptide repeat proteins, one of which is poly(GP). The hybridoma was commercially generated with funds from the Target ALS Foundation.

Collections :

Human,Neurodevelopment

Search Keywords :

Target ALS Foundation, GP dipeptide repeat proteins, poly(GP), Human, MIgG, Human, C9ORF72, , , Monoclonal, Human/Neurodevelopment, Immunohistochemistry/Western blot, RAN translation

Antigen Molecular Weight :

The molecular weight will depend on the number of GP dipeptide repeats making up the protein.

Gene :

C9ORF72

Uniprot ID :

Q96LT7

Immunogen :

H2N-C(DPEG4) GPGPGPGPGPGPGPGP

Immunogen Sequence :

GPGPGPGPGPGPGPGP

Clonality :

Monoclonal

Epitope Mapped :

Recommended Applications :

Immunohistochemistry,Western Blot

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage