p53 | Developmental Studies Hybridoma Bank p53 25F4 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

p53

catalog :

p53 25F4

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

p53 25F4

reactivity :

fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 7

Reference
D Brot A, Kurtz P, Regan E, Jakubowski B, Abrams J. A platform for interrogating cancer-associated p53 alleles. Oncogene. 2017;36:286-291 pubmed publisher
Simón R, Aparicio R, Housden B, Bray S, Busturia A. Drosophila p53 controls Notch expression and balances apoptosis and proliferation. Apoptosis. 2014;19:1430-43 pubmed publisher
Zhang C, Hong Z, Ma W, Ma D, Qian Y, Xie W, et al. Drosophila UTX coordinates with p53 to regulate ku80 expression in response to DNA damage. PLoS ONE. 2013;8:e78652 pubmed publisher
Moon S, Chung Y. p53 and PI3K/AKT signalings are up-regulated in flies with defects in the THO complex. Mol Cells. 2013;35:261-8 pubmed publisher
Monk A, Abud H, Hime G. Dmp53 is sequestered to nuclear bodies in spermatogonia of Drosophila melanogaster. Cell Tissue Res. 2012;350:385-94 pubmed publisher
Dichtel Danjoy M, Ma D, Dourlen P, Chatelain G, Napoletano F, Robin M, et al. Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. Cell Death Differ. 2013;20:108-16 pubmed publisher
Brodsky M, Weinert B, Tsang G, Rong Y, McGinnis N, Golic K, et al. Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol Cell Biol. 2004;24:1219-31 pubmed

product information

Internal ID :

1903

Name :

p53 25F4

Depositor Name :

Rubin, G.M.

Depositor Institution :

University of California at Berkeley

Date Deposited :

8/2/06

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

p53

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG2a, lambda light chain

Isotype for catalog (legacy) :

IgG2a, lambda light chain

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

14729967

Collections :

Cell signaling,Drosophila antigens,Transcription factors

Search Keywords :

Rubin, G.M., p53, Drosophila, MIgG2a, lambda light chain, Drosophila, p53, CG33336, prac, AB_579787, monoclonal, Transcription factors/Drosophila antigens/Cell signaling, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Multiple isoforms of different MW; Apparent 50 kDa

Gene :

p53

Alternate Gene Name(s) :

CG33336, prac

Uniprot ID :

Q9N6D8

Antibody Registry ID :

AB_579787

Immunogen :

Recombinant GST fusion protein of Drosophila p53 (aa 282-386 [Uniprot ID Q9N6D8]; common to all isoforms)

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Myeloma Strain :

P3XAg8.653

Epitope Mapped :

Yes

Epitope Location or Sequence :

aa 282-386

Epitope Map PubMed ID :

14729967

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunofluorescence Pubmed IDs :

24858703 23475424 22898807 26996664 22961348 30393075

Western Blot Pubmed IDs :

22898807 24265704

Immunoprecipitation Pubmed IDs :

24265704

Additional Information :

This antibody recognizes the C-terminal region common to all Drosophila p53 isoforms. p53 is the homolog of the Cellular tumor antigen p53.

DSHB Growth Medium :

Iscove's

References (legacy) :

Mol. Cell. Biol. 24, 1219-1231.; Cell 101, 103-113.

more info or order :

Developmental Studies Hybridoma Bank product webpage