product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
orb protein
catalog :
orb 4H8
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
orb 4H8
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 17
Reference |
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Chicoine J, Benoit P, Gamberi C, Paliouras M, Simonelig M, Lasko P. Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Dev Cell. 2007;13:691-704 pubmed
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Penn J, Schedl P. The master switch gene sex-lethal promotes female development by negatively regulating the N-signaling pathway. Dev Cell. 2007;12:275-86 pubmed
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Manheim E, McKim K. The Synaptonemal complex component C(2)M regulates meiotic crossing over in Drosophila. Curr Biol. 2003;13:276-85 pubmed
|
Martin S, St Johnston D. A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature. 2003;421:379-84 pubmed
|
Lantz V, Chang J, Horabin J, Bopp D, Schedl P. The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity. Genes Dev. 1994;8:598-613 pubmed
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product information
Internal ID :
2060
Name :
orb 4H8
Depositor Name :
Schedl, P.
Depositor Institution :
Princeton University
Date Deposited :
3/16/99
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
orb protein
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1, lambda light chain
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
7523244
Collections :
Drosophila antigens
Search Keywords :
Schedl, P., orb protein, Drosophila, MIgG1, lambda light chain, Drosophila, orb, CG10868, AB_528418, monoclonal, Drosophila antigens, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation
Antigen Molecular Weight :
Multiple isoforms; major bands have an apparent MW between 97 and 100 kDa
Gene :
orb
Alternate Gene Name(s) :
CG10868
Uniprot ID :
Q9VCN7
Antibody Registry ID :
AB_528418
Immunogen :
Recombinant fusion protein of phage T7 gene Phi10 and Oo18 RNA-binding protein (aa 94-765 of 915 aa isoform [Uniprot ID Q9VCN7])
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
Sp2/0
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 94-765 of 915 aa isoform [Uniprot ID Q9VCN7], containing the rrm (RNA recognition motif) regions
Epitope Map PubMed ID :
7523244
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunofluorescence Pubmed IDs :
23209437 7523244 12540903 22164257 12593793 22509132 18528333 22453833 25572421 17276344 17981137 19789180 19750210 25849588 31292144
Western Blot Pubmed IDs :
23209437 27320195 7523244 22164257 24069162
Immunoprecipitation Pubmed IDs :
22164257 24069162
Additional Information :
orb is a RNA binding protein
DSHB Growth Medium :
Iscove's
References (legacy) :
Genes Dev. 8, 598-613.
more info or order :
company information
Developmental Studies Hybridoma Bank
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