product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Dachshund protein
catalog :
mAbdac2-3
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAbdac2-3
reactivity :
mouse, Drosophila melanogaster
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 32
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; Drosophila melanogaster; 1:50
Moris Sanz M, Estacio Gómez A, Sánchez Herrero E, Díaz Benjumea F. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015;4:1132-42 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Bras Pereira C, Casares F, Janody F. The retinal determination gene Dachshund restricts cell proliferation by limiting the activity of the Homothorax-Yorkie complex. Development. 2015;142:1470-9 pubmed publisher
  • immunohistochemistry; Drosophila melanogaster; 1:50
Moris Sanz M, Estacio Gómez A, Alvarez Rivero J, Diaz Benjumea F. Specification of neuronal subtypes by different levels of Hunchback. Development. 2014;141:4366-74 pubmed publisher
Moss Taylor L, Upadhyay A, Pan X, Kim M, O Connor M. Body Size and Tissue-Scaling Is Regulated by Motoneuron-Derived Activinß in Drosophila melanogaster. Genetics. 2019;213:1447-1464 pubmed publisher
Bridi J, Ludlow Z, Hirth F. Lineage-specific determination of ring neuron circuitry in the central complex of Drosophila. Biol Open. 2019;8: pubmed publisher
Riddiford L, Truman J, Nern A. Juvenile hormone reveals mosaic developmental programs in the metamorphosing optic lobe of Drosophila melanogaster. Biol Open. 2018;7: pubmed publisher
Li S, Koe C, Tay S, Tan A, Zhang S, Zhang Y, et al. An intrinsic mechanism controls reactivation of neural stem cells by spindle matrix proteins. Nat Commun. 2017;8:122 pubmed publisher
Aggarwal P, Gera J, Ghosh S, Mandal L, Mandal S. Noncanonical Decapentaplegic Signaling Activates Matrix Metalloproteinase 1 To Restrict Hedgehog Activity and Limit Ectopic Eye Differentiation in Drosophila. Genetics. 2017;207:197-213 pubmed publisher
Daniele J, Chu T, Kunes S. A novel proteolytic event controls Hedgehog intracellular sorting and distribution to receptive fields. Biol Open. 2017;6:540-550 pubmed publisher
Apitz H, Salecker I. A region-specific neurogenesis mode requires migratory progenitors in the Drosophila visual system. Nat Neurosci. 2015;18:46-55 pubmed publisher
Chen X, Quan Y, Wang H, Luo H. Trehalase regulates neuroepithelial stem cell maintenance and differentiation in the Drosophila optic lobe. PLoS ONE. 2014;9:e101433 pubmed publisher
Lacin H, Rusch J, Yeh R, Fujioka M, Wilson B, Zhu Y, et al. Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D. Dev Biol. 2014;388:117-33 pubmed publisher
Zhou L, Luo H. Replication protein a links cell cycle progression and the onset of neurogenesis in Drosophila optic lobe development. J Neurosci. 2013;33:2873-88 pubmed publisher
Li Y, Padgett R. bantam is required for optic lobe development and glial cell proliferation. PLoS ONE. 2012;7:e32910 pubmed publisher
Hwang H, Rulifson E. Serial specification of diverse neuroblast identities from a neurogenic placode by Notch and Egfr signaling. Development. 2011;138:2883-93 pubmed publisher
Goossens T, Kang Y, Wuytens G, Zimmermann P, Callaerts Vegh Z, Pollarolo G, et al. The Drosophila L1CAM homolog Neuroglian signals through distinct pathways to control different aspects of mushroom body axon development. Development. 2011;138:1595-605 pubmed publisher
Wang W, Liu W, Wang Y, Zhou L, Tang X, Luo H. Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development. Dev Biol. 2011;350:414-28 pubmed publisher
Yasugi T, Sugie A, Umetsu D, Tabata T. Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe. Development. 2010;137:3193-203 pubmed publisher
Ngo K, Wang J, Junker M, Kriz S, Vo G, Asem B, et al. Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe. Dev Biol. 2010;346:284-95 pubmed publisher
Sawamura N, Ando T, Maruyama Y, Fujimuro M, Mochizuki H, Honjo K, et al. Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. Mol Psychiatry. 2008;13:1138-48, 1069 pubmed publisher
Hoopfer E, Penton A, Watts R, Luo L. Genomic analysis of Drosophila neuronal remodeling: a role for the RNA-binding protein Boule as a negative regulator of axon pruning. J Neurosci. 2008;28:6092-103 pubmed publisher
Yasugi T, Umetsu D, Murakami S, Sato M, Tabata T. Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT. Development. 2008;135:1471-80 pubmed publisher
Zhu C, Boone J, Jensen P, Hanna S, Podemski L, Locke J, et al. Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain. Development. 2008;135:513-21 pubmed publisher
Tanaka Matakatsu M, Du W. Direct control of the proneural gene atonal by retinal determination factors during Drosophila eye development. Dev Biol. 2008;313:787-801 pubmed
Wang S, Tulina N, Carlin D, Rulifson E. The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axis. Proc Natl Acad Sci U S A. 2007;104:19873-8 pubmed
Knox S, Ge H, Dimitroff B, Ren Y, Howe K, Arsham A, et al. Mechanisms of TSC-mediated control of synapse assembly and axon guidance. PLoS ONE. 2007;2:e375 pubmed
Umetsu D, Murakami S, Sato M, Tabata T. The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system. Development. 2006;133:791-800 pubmed
Pappu K, Ostrin E, Middlebrooks B, Sili B, Chen R, Atkins M, et al. Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund. Development. 2005;132:2895-905 pubmed
Adachi Yamada T, Harumoto T, Sakurai K, Ueda R, Saigo K, O Connor M, et al. Wing-to-Leg homeosis by spineless causes apoptosis regulated by Fish-lips, a novel leucine-rich repeat transmembrane protein. Mol Cell Biol. 2005;25:3140-50 pubmed
Dominguez M, Ferres Marco D, Gutiérrez Aviñó F, Speicher S, Beneyto M. Growth and specification of the eye are controlled independently by Eyegone and Eyeless in Drosophila melanogaster. Nat Genet. 2004;36:31-9 pubmed
Goto S, Hayashi S. Proximal to distal cell communication in the Drosophila leg provides a basis for an intercalary mechanism of limb patterning. Development. 1999;126:3407-13 pubmed
Mardon G, Solomon N, Rubin G. dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila. Development. 1994;120:3473-86 pubmed
product information
Internal ID :
1659
Name :
mAbdac2-3
Depositor Name :
Rubin, G.M.
Depositor Institution :
University of California at Berkeley
Depositor Website :
https://www.janelia.org/lab/rubin-lab
Date Deposited :
7/15/98
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Dachshund protein
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
7821215
Collections :
Drosophila antigens,Nucleus,Transcription factors
Search Keywords :
Rubin, G.M., Dachshund protein, Drosophila, MIgG1, kappa light chain, Drosophila, dac, Dmel_CG4952, AB_528190, Monoclonal , Drosophila antigens/Transcription factors/Nucleus, Immunohistochemistry/Immunofluorescence
Antigen Molecular Weight :
113.6 kDa
Gene :
dac
Alternate Gene Name(s) :
Dmel_CG4952
Uniprot ID :
Q24030
Antibody Registry ID :
AB_528190
Immunogen :
Recombinant protein domain
Immunogen Sequence :
a.a. 378-599
Clonality :
Monoclonal
Myeloma Strain :
P3x63Ag8.653
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence,Immunohistochemistry
Immunohistochemistry Pubmed IDs :
7821215 14702038 15930118 16439478 17440611 18056636 21653613 24512689 26276099 28744001
Immunofluorescence Pubmed IDs :
10393119 14702038 15798200 15930118 18083159 18171686 18339672 18550751 18762802 20724446 20692248 21146517 21389050 22412948 23407946 25003205 25344076 25501037
Additional Information :
FBgn0005677. RRID: AB_528190
DSHB Growth Medium :
Iscove's
References (legacy) :
Development 120, 3473-3486.; Development 126, 3407-3413.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US