High affinity IgG Fc receptor I/ CD64 | Developmental Studies Hybridoma Bank mAB 197 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

High affinity IgG Fc receptor I/ CD64

catalog :

mAB 197

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

mAB 197

reactivity :

human

application :

ELISA, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

product information

Internal ID :

34938

Name :

mAB 197

Depositor Name :

Guyre, Paul M.

Depositor Institution :

Geisel School of Medicine at Dartmouth

Depositor Website :

https://graduate.dartmouth.edu/pemm/people/paul-m-guyre

Date Deposited :

4/23/19

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

High affinity IgG Fc receptor I/ CD64

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG2a

Positive Tested Species Reactivity :

Human

Depositor Notes (Special Instructions) :

mAb 197 triggers a oxidative burst response

Collections :

CD antigens,Human

Search Keywords :

Guyre, Paul M., High affinity IgG Fc receptor I/ CD64, Human, MIgG2a, Human, FCGR1A, CD64, CD64A, FCG1, FCGR1, IGFR1, , Monoclonal, Human/CD antigens, FACS/Immunofluorescence/Function blocking/Immunoprecipitation/ELISA

Antigen Molecular Weight :

42.6 kDa

Gene :

FCGR1A

Alternate Gene Name(s) :

CD64, CD64A, FCG1, FCGR1, IGFR1

Uniprot ID :

P12314

Immunogen :

Mononuclear leukocytes

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

NS-1

Epitope Mapped :

Yes

Epitope Location or Sequence :

mAB 197 binds to FcyRl by both its FC and F(ab) domains; trivalent

Epitope Map PubMed ID :

2474608

Recommended Applications :

ELISA,FACS,Function Blocking,Immunofluorescence,Immunoprecipitation

Immunofluorescence Pubmed IDs :

8616043 1703798

Immunoprecipitation Pubmed IDs :

10514529 8064233 8327478

ELISA Pubmed IDs :

12439607

Function Blocking Pubmed IDs :

1703798 8616043 2474608 2547782 1431118 7687898 11714794

FACS Pubmed IDs :

2494265 1703798 8616043 2474608 12439607

Depositor Growth Medium :

RPMI 1640 medium supplemented with 10% FBS, 2 mM glutamine, and 50 ug/ml gentamicin at 37°C

Additional Information :

Patent 4,954,617. Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage