Eyes Absent (Eya) protein | Developmental Studies Hybridoma Bank eya10H6 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Eyes Absent (Eya) protein

catalog :

eya10H6

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

eya10H6

reactivity :

fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 64

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; fruit fly; fig 1i	Ulmschneider B, Grillo Hill B, Benitez M, Azimova D, Barber D, Nystul T. Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation. J Cell Biol. 2016;215:345-355 pubmed
immunocytochemistry; fruit fly; 1:100; fig 1	Piñeiro C, Lopes C, Casares F. A conserved transcriptional network regulates lamina development in the Drosophila visual system. Development. 2014;141:2838-47 pubmed publisher
	Fernández Espartero C, Rizzo A, Fulford A, Falo Sanjuan J, Goutte Gattat D, Ribeiro P. Prp8 regulates oncogene-induced hyperplastic growth in Drosophila. Development. 2018;145: pubmed publisher
	Shaw R, Kottler B, Ludlow Z, Buhl E, Kim D, Morais da Silva S, et al. In vivo expansion of functionally integrated GABAergic interneurons by targeted increase in neural progenitors. EMBO J. 2018;37: pubmed publisher
	Borensztejn A, Mascaro A, Wharton K. JAK/STAT signaling prevents excessive apoptosis to ensure maintenance of the interfollicular stalk critical for Drosophila oogenesis. Dev Biol. 2018;438:1-9 pubmed publisher
	Zhu J, Ordway A, Weber L, Buddika K, Kumar J. Polycomb group (PcG) proteins and Pax6 cooperate to inhibit in vivo reprogramming of the developing Drosophila eye. Development. 2018;145: pubmed publisher
	Morrison C, Chen H, Cook T, Brown S, Treisman J. Glass promotes the differentiation of neuronal and non-neuronal cell types in the Drosophila eye. PLoS Genet. 2018;14:e1007173 pubmed publisher
	Dai W, Peterson A, Kenney T, Burrous H, Montell D. Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate. Nat Commun. 2017;8:1244 pubmed publisher
	LeBlanc M, Lehmann R. Domain-specific control of germ cell polarity and migration by multifunction Tre1 GPCR. J Cell Biol. 2017;216:2945-2958 pubmed publisher
	Stratmann J, Thor S. Neuronal cell fate specification by the molecular convergence of different spatio-temporal cues on a common initiator terminal selector gene. PLoS Genet. 2017;13:e1006729 pubmed publisher
	Zhou Q, Yu L, Friedrich M, Pignoni F. Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye. Dev Biol. 2017;421:67-76 pubmed publisher
	Stratmann J, Gabilondo H, Benito Sipos J, Thor S. Neuronal cell fate diversification controlled by sub-temporal action of Kruppel. elife. 2016;5: pubmed publisher
	Bahrampour S, Thor S. Ctr9, a Key Component of the Paf1 Complex, Affects Proliferation and Terminal Differentiation in the Developing Drosophila Nervous System. G3 (Bethesda). 2016;6:3229-3239 pubmed publisher
	Gabilondo H, Stratmann J, Rubio Ferrera I, Millán Crespo I, Contero García P, Bahrampour S, et al. Neuronal Cell Fate Specification by the Convergence of Different Spatiotemporal Cues on a Common Terminal Selector Cascade. PLoS Biol. 2016;14:e1002450 pubmed publisher
	Aguilar Hidalgo D, Becerra Alonso D, García Morales D, Casares F. Toward a study of gene regulatory constraints to morphological evolution of the Drosophila ocellar region. Dev Genes Evol. 2016;226:221-33 pubmed publisher
	Wingert L, Dinardo S. Traffic jam functions in a branched pathway from Notch activation to niche cell fate. Development. 2015;142:2268-77 pubmed publisher
	Bivik C, Bahrampour S, Ulvklo C, Nilsson P, Angel A, Fransson F, et al. Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells. Genetics. 2015;200:1229-44 pubmed publisher
	Manning L, Weideman A, Peercy B, Starz Gaiano M. Tissue landscape alters adjacent cell fates during Drosophila egg development. Nat Commun. 2015;6:7356 pubmed publisher
	Qian Y, Dominado N, Zoller R, Ng C, Kudyba K, Siddall N, et al. Ecdysone signaling opposes epidermal growth factor signaling in regulating cyst differentiation in the male gonad of Drosophila melanogaster. Dev Biol. 2014;394:217-27 pubmed publisher
	Shields A, Spence A, Yamashita Y, Davies E, Fuller M. The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells. Development. 2014;141:73-82 pubmed publisher
	Chang Y, Jang A, Lin C, Montell D. Castor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesis. Proc Natl Acad Sci U S A. 2013;110:E1734-42 pubmed publisher
	Jin M, Jusiak B, Bai Z, Mardon G. Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survival. PLoS ONE. 2013;8:e58818 pubmed publisher
	Gómez J, Wang Y, Riechmann V. Tao controls epithelial morphogenesis by promoting Fasciclin 2 endocytosis. J Cell Biol. 2012;199:1131-43 pubmed publisher
	Jusiak B, Abulimiti A, Haelterman N, Chen R, Mardon G. MAPK target sites of eyes absent are not required for eye development or survival in Drosophila. PLoS ONE. 2012;7:e50776 pubmed publisher
	Renault A. vasa is expressed in somatic cells of the embryonic gonad in a sex-specific manner in Drosophila melanogaster. Biol Open. 2012;1:1043-8 pubmed publisher
	Aguilar Hidalgo D, Domínguez Cejudo M, Amore G, Brockmann A, Lemos M, Cordoba A, et al. A Hh-driven gene network controls specification, pattern and size of the Drosophila simple eyes. Development. 2013;140:82-92 pubmed publisher
	De Graeve F, Van De Bor V, Ghiglione C, Cerezo D, Jouandin P, Ueda R, et al. Drosophila apc regulates delamination of invasive epithelial clusters. Dev Biol. 2012;368:76-85 pubmed publisher
	Aumiller V, Graebsch A, Kremmer E, Niessing D, Forstemann K. Drosophila Pur-? binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte. RNA Biol. 2012;9:633-43 pubmed publisher
	Wong C, Jones D. Efficiency of spermatogonial dedifferentiation during aging. PLoS ONE. 2012;7:e33635 pubmed publisher
	Eade K, Fancher H, Ridyard M, Allan D. Developmental transcriptional networks are required to maintain neuronal subtype identity in the mature nervous system. PLoS Genet. 2012;8:e1002501 pubmed publisher
	Ulvklo C, Macdonald R, Bivik C, Baumgardt M, Karlsson D, Thor S. Control of neuronal cell fate and number by integration of distinct daughter cell proliferation modes with temporal progression. Development. 2012;139:678-89 pubmed publisher
	Benito Sipos J, Ulvklo C, Gabilondo H, Baumgardt M, Angel A, Torroja L, et al. Seven up acts as a temporal factor during two different stages of neuroblast 5-6 development. Development. 2011;138:5311-20 pubmed publisher
	Casper A, Baxter K, Van Doren M. no child left behind encodes a novel chromatin factor required for germline stem cell maintenance in males but not females. Development. 2011;138:3357-66 pubmed publisher
	Weyers J, Milutinovich A, Takeda Y, Jemc J, Van Doren M. A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol. 2011;353:217-28 pubmed publisher
	Brockmann A, Domínguez Cejudo M, Amore G, Casares F. Regulation of ocellar specification and size by twin of eyeless and homothorax. Dev Dyn. 2011;240:75-85 pubmed publisher
	Karlsson D, Baumgardt M, Thor S. Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cues. PLoS Biol. 2010;8:e1000368 pubmed publisher
	Singh S, Zheng Z, Wang H, Oh S, Chen X, Hou S. Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling. J Cell Physiol. 2010;223:500-10 pubmed publisher
	Sheng X, Brawley C, MATUNIS E. Dedifferentiating spermatogonia outcompete somatic stem cells for niche occupancy in the Drosophila testis. Cell Stem Cell. 2009;5:191-203 pubmed publisher
	Eade K, Allan D. Neuronal phenotype in the mature nervous system is maintained by persistent retrograde bone morphogenetic protein signaling. J Neurosci. 2009;29:3852-64 pubmed publisher
	Firth L, Baker N. Retinal determination genes as targets and possible effectors of extracellular signals. Dev Biol. 2009;327:366-75 pubmed publisher
	Siera S, Cline T. Sexual back talk with evolutionary implications: stimulation of the Drosophila sex-determination gene sex-lethal by its target transformer. Genetics. 2008;180:1963-81 pubmed publisher
	Braid L, Verheyen E. Drosophila nemo promotes eye specification directed by the retinal determination gene network. Genetics. 2008;180:283-99 pubmed publisher
	Ghiglione C, Devergne O, Cerezo D, Noselli S. Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles. EMBO Rep. 2008;9:676-82 pubmed publisher
	DeFalco T, Camara N, Le Bras S, Van Doren M. Nonautonomous sex determination controls sexually dimorphic development of the Drosophila gonad. Dev Cell. 2008;14:275-86 pubmed publisher
	Tanaka Matakatsu M, Du W. Direct control of the proneural gene atonal by retinal determination factors during Drosophila eye development. Dev Biol. 2008;313:787-801 pubmed
	Hempel L, Oliver B. Sex-specific DoublesexM expression in subsets of Drosophila somatic gonad cells. BMC Dev Biol. 2007;7:113 pubmed
	Sun J, Deng W. Hindsight mediates the role of notch in suppressing hedgehog signaling and cell proliferation. Dev Cell. 2007;12:431-42 pubmed
	Assa Kunik E, Torres I, Schejter E, Johnston D, Shilo B. Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development. 2007;134:1161-9 pubmed
	Baumgardt M, Miguel Aliaga I, Karlsson D, Ekman H, Thor S. Specification of neuronal identities by feedforward combinatorial coding. PLoS Biol. 2007;5:e37 pubmed
	Penn J, Schedl P. The master switch gene sex-lethal promotes female development by negatively regulating the N-signaling pathway. Dev Cell. 2007;12:275-86 pubmed
	Le Bras S, Van Doren M. Development of the male germline stem cell niche in Drosophila. Dev Biol. 2006;294:92-103 pubmed
	Mathews W, Ong D, Milutinovich A, Van Doren M. Zinc transport activity of Fear of Intimacy is essential for proper gonad morphogenesis and DE-cadherin expression. Development. 2006;133:1143-53 pubmed
	Adam J, Montell D. A role for extra macrochaetae downstream of Notch in follicle cell differentiation. Development. 2004;131:5971-80 pubmed
	Miguel Aliaga I, Allan D, Thor S. Independent roles of the dachshund and eyes absent genes in BMP signaling, axon pathfinding and neuronal specification. Development. 2004;131:5837-48 pubmed
	DeFalco T, Le Bras S, Van Doren M. Abdominal-B is essential for proper sexually dimorphic development of the Drosophila gonad. Mech Dev. 2004;121:1323-33 pubmed
	Kablar B. MyoD-lacZ transgenes are early markers in the neural retina, but MyoD function appears to be inhibited in the developing retinal cells. Int J Dev Neurosci. 2004;22:215-24 pubmed
	Torres I, Lopez Schier H, St Johnston D. A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila. Dev Cell. 2003;5:547-58 pubmed
	Jenkins A, McCaffery J, Van Doren M. Drosophila E-cadherin is essential for proper germ cell-soma interaction during gonad morphogenesis. Development. 2003;130:4417-26 pubmed
	Fabrizio J, Boyle M, Dinardo S. A somatic role for eyes absent (eya) and sine oculis (so) in Drosophila spermatocyte development. Dev Biol. 2003;258:117-28 pubmed
	Pappu K, Chen R, Middlebrooks B, Woo C, Heberlein U, Mardon G. Mechanism of hedgehog signaling during Drosophila eye development. Development. 2003;130:3053-62 pubmed
	Kauffman T, Tran J, Dinardo S. Mutations in Nop60B, the Drosophila homolog of human dyskeratosis congenita 1, affect the maintenance of the germ-line stem cell lineage during spermatogenesis. Dev Biol. 2003;253:189-99 pubmed
	Bai J, Montell D. Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis. Development. 2002;129:5377-88 pubmed
	Perez M, Paulson H, Pendse S, Saionz S, Bonini N, Pittman R. Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation. J Cell Biol. 1998;143:1457-70 pubmed
	Boyle M, Bonini N, DiNardo S. Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm. Development. 1997;124:971-82 pubmed

product information

Internal ID :

933

Name :

eya10H6

Depositor Name :

Benzer, S. / Bonini, N.M.

Depositor Institution :

California Institute of Technology

Date Deposited :

2/17/00

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Eyes Absent (Eya) protein

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila,Xenopus

Species Tested (legacy) :

Drosophila, Xenopus

Initial Publication Pubmed ID :

9056773

Depositor Notes (Special Instructions) :

Fusion: 1/28/93.

Collections :

Cell markers,Drosophila antigens,Enzymes,Neurodevelopment,Nucleus,Transcription factors,Xenopus

Search Keywords :

Benzer, Seymour / Bonini, N.M., Eyes Absent (Eya) protein, Drosophila, MIgG1, Drosophila/Xenopus, eya, eyes absent; cli, AB_528232, monoclonal, Nucleus/Cell markers/Drosophila antigens/Enzymes/Neurodevelopment/Xenopus, Immunohistochemistry/Immunofluorescence/Western Blot

Antigen Molecular Weight :

Predicted; 80 or 81kDa; Apparent: 94kDa

Gene :

eya

Alternate Gene Name(s) :

eyes absent; cli

Uniprot ID :

Q05201

Antibody Registry ID :

AB_528232

Immunogen :

Peptide TGRARGRRHQQPSP from Drosophila Eyes Absent (Eya) protein

Immunogen Sequence :

aa 462-475

Clonality :

Monoclonal

Myeloma Strain :

HL-1

Epitope Mapped :

Yes

Epitope Location or Sequence :

aa 462-475 (TGRARGRRHQQPSP)

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

9056773 12756186 15245757 27148744 31447264

Immunofluorescence Pubmed IDs :

9852144 12781687 16566915 12900457 22627290 15454263 17336908 16481356 12756186 17298176 21752937 21377458 12403709 18845845 19135045 19664993 22241838 15539491 22071101 23554934 18267095 21104743 25169192 17276344 23610413 23251383 23154412 20485487 22614836 18757943 17332535 24346697 15525669 20143337 23213382 18552769 22383890 18083159 12645924 19321782 14536057 27693434 29093440 29324767 29530880

Depositor Growth Medium :

RPMI

Additional Information :

The eya gene product is a tyrosine phosphatase involved in transcription regulation during organogenesis. eya is essential in eye development and is required for the survival of eye progenitor cells.

DSHB Growth Medium :

Iscove's

References (legacy) :

Cell 72, 379-395.; Development 140(1), 82-92.

more info or order :

Developmental Studies Hybridoma Bank product webpage