product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Fly Bag-of-marbles
catalog :
bam
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
bam
reactivity :
fruit fly
application :
immunocytochemistry
citations: 13
Reference
Tang Y, Geng Q, Chen D, Zhao S, Liu X, Wang Z. Germline Proliferation Is Regulated by Somatic Endocytic Genes via JNK and BMP Signaling in Drosophila. Genetics. 2017;206:189-197 pubmed publisher
Chen D, Wu C, Zhao S, Geng Q, Gao Y, Li X, et al. Three RNA binding proteins form a complex to promote differentiation of germline stem cell lineage in Drosophila. PLoS Genet. 2014;10:e1004797 pubmed publisher
Yan D, Neumüller R, BUCKNER M, Ayers K, Li H, Hu Y, et al. A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014;28:459-73 pubmed publisher
Xin T, Xuan T, Tan J, Li M, Zhao G, Li M. The Drosophila putative histone acetyltransferase Enok maintains female germline stem cells through regulating Bruno and the niche. Dev Biol. 2013;384:1-12 pubmed publisher
Jin Z, Flynt A, Lai E. Drosophila piwi mutants exhibit germline stem cell tumors that are sustained by elevated Dpp signaling. Curr Biol. 2013;23:1442-8 pubmed publisher
Xuan T, Xin T, He J, Tan J, Gao Y, Feng S, et al. dBre1/dSet1-dependent pathway for histone H3K4 trimethylation has essential roles in controlling germline stem cell maintenance and germ cell differentiation in the Drosophila ovary. Dev Biol. 2013;379:167-81 pubmed publisher
Li Y, Zhang Q, Carreira Rosario A, Maines J, McKearin D, Buszczak M. Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary. PLoS ONE. 2013;8:e58301 pubmed publisher
Eun S, Stoiber P, Wright H, McMurdie K, Choi C, Gan Q, et al. MicroRNAs downregulate Bag of marbles to ensure proper terminal differentiation in the Drosophila male germline. Development. 2013;140:23-30 pubmed publisher
Lim J, Fuller M. Somatic cell lineage is required for differentiation and not maintenance of germline stem cells in Drosophila testes. Proc Natl Acad Sci U S A. 2012;109:18477-81 pubmed publisher
Monk A, Abud H, Hime G. Dmp53 is sequestered to nuclear bodies in spermatogonia of Drosophila melanogaster. Cell Tissue Res. 2012;350:385-94 pubmed publisher
Li Y, Maines J, Tastan O, McKearin D, Buszczak M. Mei-P26 regulates the maintenance of ovarian germline stem cells by promoting BMP signaling. Development. 2012;139:1547-56 pubmed publisher
Tokusumi T, Tokusumi Y, Hopkins D, Shoue D, Corona L, Schulz R. Germ line differentiation factor Bag of Marbles is a regulator of hematopoietic progenitor maintenance during Drosophila hematopoiesis. Development. 2011;138:3879-84 pubmed publisher
Li Y, Minor N, Park J, McKearin D, Maines J. Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance. Proc Natl Acad Sci U S A. 2009;106:9304-9 pubmed publisher
product information
Internal ID :
5861
Name :
bam
Depositor Name :
McKearin, D.
Depositor Institution :
Howard Hughes Medical Institute
Date Deposited :
3/31/09
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Fly Bag-of-marbles
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
19470484
Depositor Notes (Special Instructions) :
Weakly positive in western blots.
Collections :
Drosophila antigens
Search Keywords :
McKearin, D., Fly Bag-of-marbles, Drosophila, MIgG1, Drosophila, bam, CG10422, BamC, AB_10570327, monoclonal, Drosophila antigens, Immunofluorescence
Antigen Molecular Weight :
Predicted: 50 kDa; Apparent: 55kDa
Gene :
bam
Alternate Gene Name(s) :
CG10422, BamC
Uniprot ID :
P22745
Antibody Registry ID :
AB_10570327
Synonyms (Alternate Clone Names) :
anti-BamC
Immunogen :
Recombinant Bag-of-marbles protein fragment fused to His-tag
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence
Immunoblotting (legacy) :
poor
Immunofluorescence Pubmed IDs :
19470484 23091022 23891114 22961348 23624310 24120347 22438571 23526974 21813570 24576427 23154414 31295251
DSHB Growth Medium :
Iscove's
References (legacy) :
Development 121, 2937-2947.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US