dFmr1 protein | Developmental Studies Hybridoma Bank anti-dFMR1, 5A11 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

dFmr1 protein

catalog :

anti-dFMR1, 5A11

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

anti-dFMR1, 5A11

reactivity :

fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; fruit fly; 1:100; loading ...; fig 4f	Stepien B, Oppitz C, Gerlach D, Dag U, Novatchkova M, Krüttner S, et al. RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2. Proc Natl Acad Sci U S A. 2016;113:E7030-E7038 pubmed publisher
immunocytochemistry; fruit fly; 1:10; fig 3	Zacharogianni M, Aguilera Gomez A, Veenendaal T, Smout J, Rabouille C. A stress assembly that confers cell viability by preserving ERES components during amino-acid starvation. elife. 2014;3: pubmed publisher
	Jevtov I, Zacharogianni M, van Oorschot M, van Zadelhoff G, Aguilera Gomez A, Vuillez I, et al. TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules. J Cell Sci. 2015;128:2497-508 pubmed publisher
	Bozzetti M, Specchia V, Cattenoz P, Laneve P, Geusa A, Sahin H, et al. The Drosophila fragile X mental retardation protein participates in the piRNA pathway. J Cell Sci. 2015;128:2070-84 pubmed publisher
	Sudhakaran I, Hillebrand J, Dervan A, Das S, Holohan E, H lsmeier J, et al. FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control. Proc Natl Acad Sci U S A. 2014;111:E99-E108 pubmed publisher
	Bianco A, Dienstbier M, Salter H, Gatto G, Bullock S. Bicaudal-D regulates fragile X mental retardation protein levels, motility, and function during neuronal morphogenesis. Curr Biol. 2010;20:1487-92 pubmed publisher
	Banerjee P, Schoenfeld B, Bell A, Choi C, Bradley M, Hinchey P, et al. Short- and long-term memory are modulated by multiple isoforms of the fragile X mental retardation protein. J Neurosci. 2010;30:6782-92 pubmed publisher
	Pepper A, Beerman R, Bhogal B, Jongens T. Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. PLoS ONE. 2009;4:e7618 pubmed publisher
	Xu X, Li Y, Wang F, Gao F. The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. J Neurosci. 2008;28:11883-9 pubmed publisher
	Sekine T, Yamaguchi T, Hamano K, Siomi H, Saez L, Ishida N, et al. Circadian phenotypes of Drosophila fragile x mutants in alternative genetic backgrounds. Zoolog Sci. 2008;25:561-71 pubmed publisher
	Reeve S, Lin X, Sahin B, Jiang F, Yao A, Liu Z, et al. Mutational analysis establishes a critical role for the N terminus of fragile X mental retardation protein FMRP. J Neurosci. 2008;28:3221-6 pubmed publisher
	Boylan K, Mische S, Li M, Marques G, Morin X, Chia W, et al. Motility screen identifies Drosophila IGF-II mRNA-binding protein--zipcode-binding protein acting in oogenesis and synaptogenesis. PLoS Genet. 2008;4:e36 pubmed publisher
	Banerjee P, Nayar S, Hebbar S, Fox C, Jacobs M, Park J, et al. Substitution of critical isoleucines in the KH domains of Drosophila fragile X protein results in partial loss-of-function phenotypes. Genetics. 2007;175:1241-50 pubmed
	Okamura K, Ishizuka A, Siomi H, Siomi M. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 2004;18:1655-66 pubmed

product information

Internal ID :

2228

Name :

anti-dFmr1, 5A11

Depositor Name :

Siomi, H.

Depositor Institution :

Keio University School of Medicine

Date Deposited :

3/5/03

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

dFmr1 protein

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

15231716

Depositor Notes (Special Instructions) :

MW: 78 kDa (+82 kDa minor band)

Collections :

Cardiac development,Drosophila antigens,Neurodevelopment,Skeletal muscle,Transcription factors

Search Keywords :

Siomi, H., dFMR1, Drosophila, MIgG1, Drosophila, Fmr1, CG6203, dFMRP, dFXR1, dFXRP, AB_528252, monoclonal, Cardiac development/Drosophila antigens/Neurodevelopment/Skeletal muscle, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Multiple isforms; Predicted: between 60 and 76 kDa

Gene :

Fmr1

Alternate Gene Name(s) :

CG6203, dFMRP, dFXR1, dFXRP

Uniprot ID :

Q9NFU0

Antibody Registry ID :

AB_528252

Immunogen :

Recombinant His-tagged dFmr1 protein

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

P3x63Ag8.653

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunofluorescence Pubmed IDs :

20463240 18282112 25908854 26054799 25386913 24344294 20691595 18354025

Western Blot Pubmed IDs :

15231716 19005053 19888420 18624566 20463240 17194772 18282112 25908854 20691595 18354025

Immunoprecipitation Pubmed IDs :

18282112 25908854

DSHB Growth Medium :

Iscove's

References (legacy) :

Genes Dev. 18, 1655-1666.

more info or order :

Developmental Studies Hybridoma Bank product webpage