product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Yan Drosophila protein
catalog :
anti-Yan 8B12H9
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
anti-Yan 8B12H9
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 7
| Reference |
|---|
Vivekanand P, Tootle T, Rebay I. MAE, a dual regulator of the EGFR signaling pathway, is a target of the Ets transcription factors PNT and YAN. Mech Dev. 2004;121:1469-79 pubmed
|
Qiao F, Song H, Kim C, Sawaya M, Hunter J, Gingery M, et al. Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell. 2004;118:163-73 pubmed
|
Ramos E, Price M, Rohrbaugh M, Lai Z. Identifying functional cis-acting regulatory modules of the yan gene in Drosophila melanogaster. Dev Genes Evol. 2003;213:83-9 pubmed
|
Tootle T, Lee P, Rebay I. CRM1-mediated nuclear export and regulated activity of the Receptor Tyrosine Kinase antagonist YAN require specific interactions with MAE. Development. 2003;130:845-57 pubmed
|
Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow M. sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell. 1998;92:253-63 pubmed
|
Rebay I, Rubin G. Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway. Cell. 1995;81:857-66 pubmed
|
product information
Internal ID :
1636
Name :
anti-Yan 8B12H9
Depositor Name :
Rubin, G.M.
Depositor Institution :
University of California
Date Deposited :
2/16/05
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Yan Drosophila protein
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
7781063
Depositor Notes (Special Instructions) :
This antibody works well for immunocytochemistry in embryos, imaginal discs and cultured cells, immunoprecipitation and Western blotting. Freezing significantly reduces the effective titre – supernatants are stable for a minimum of 5 years at 4° C with no loss of titre.
Collections :
Cell signaling,Drosophila antigens,Transcription factors
Search Keywords :
Rubin, G.M., Yan Drosophila protein, Drosophila, MIgG1, Drosophila, aop, CG3166, Yan, pok, DROYANETSB, AB_531807, monoclonal, Cell signaling/Drosophila antigens/Transcription factors, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation
Antigen Molecular Weight :
Predicted: 79 kDa
Gene :
aop
Alternate Gene Name(s) :
CG3166, Yan, pok, DROYANETSB
Uniprot ID :
Q01842
Antibody Registry ID :
AB_531807
Synonyms (Alternate Clone Names) :
8B12
Immunogen :
Recombinant GST/Yan (aa 69-388) fusion protein
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
P3x63Ag8.653
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 69-388
Epitope Map PubMed ID :
7781063
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
12632177
Immunofluorescence Pubmed IDs :
7781063 12538513 15260987 15511639 20048052 9458049
Western Blot Pubmed IDs :
7781063 12538513 20048052
Additional Information :
The Yan protein is also known as Ets DNA-binding protein pokkuri and anterior open.
DSHB Growth Medium :
Iscove's
References (legacy) :
Cell 81, 857-866.; Development 130, 845-857.; Dev. Genes Evol. 213, 83-89.; Cell 118, 163-173.; Mech. Dev. 121, 1469-1479.
more info or order :
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Developmental Studies Hybridoma Bank
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