product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Antennapedia protein
catalog :
anti-Antp 4C3
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
anti-Antp 4C3
reactivity :
fruit fly
application :
immunohistochemistry, immunocytochemistry
citations: 33
Reference
Papadopoulos D, Skouloudaki K, Engstrom Y, Terenius L, Rigler R, Zechner C, et al. Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch. Development. 2019;146: pubmed publisher
Lam V, Tokusumi T, Tokusumi Y, Schulz R. bantam miRNA is important for Drosophila blood cell homeostasis and a regulator of proliferation in the hematopoietic progenitor niche. Biochem Biophys Res Commun. 2014;453:467-72 pubmed publisher
Tong X, Hrycaj S, Podlaha O, POPADIC A, Monteiro A. Over-expression of Ultrabithorax alters embryonic body plan and wing patterns in the butterfly Bicyclus anynana. Dev Biol. 2014;394:357-66 pubmed publisher
Rogulja Ortmann A, Picao Osorio J, Villava C, Patraquim P, Lafuente E, Aspden J, et al. The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system. Development. 2014;141:2046-56 pubmed publisher
Kimoto M, Tsubota T, Uchino K, Sezutsu H, Takiya S. Hox transcription factor Antp regulates sericin-1 gene expression in the terminal differentiated silk gland of Bombyx mori. Dev Biol. 2014;386:64-71 pubmed publisher
Lim Y, Yamasaki Y, Tsuda L. Ebi alleviates excessive growth signaling through multiple epigenetic functions in Drosophila. Genes Cells. 2013;18:909-20 pubmed publisher
Oliver J, Tong X, Gall L, Piel W, Monteiro A. A single origin for nymphalid butterfly eyespots followed by widespread loss of associated gene expression. PLoS Genet. 2012;8:e1002893 pubmed publisher
Tokusumi Y, Tokusumi T, Shoue D, Schulz R. Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland. PLoS ONE. 2012;7:e41604 pubmed publisher
Lemons D, Pare A, McGinnis W. Three Drosophila Hox complex microRNAs do not have major effects on expression of evolutionarily conserved Hox gene targets during embryogenesis. PLoS ONE. 2012;7:e31365 pubmed publisher
Kulkarni V, Khadilkar R, Magadi S, Srivathsa M, Inamdar M. Asrij maintains the stem cell niche and controls differentiation during Drosophila lymph gland hematopoiesis. PLoS ONE. 2011;6:e27667 pubmed publisher
Merabet S, Litim Mecheri I, Karlsson D, Dixit R, Saadaoui M, Monier B, et al. Insights into Hox protein function from a large scale combinatorial analysis of protein domains. PLoS Genet. 2011;7:e1002302 pubmed publisher
Minakhina S, Tan W, Steward R. JAK/STAT and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila. Dev Biol. 2011;352:308-16 pubmed publisher
Tokusumi Y, Tokusumi T, Stoller Conrad J, Schulz R. Serpent, suppressor of hairless and U-shaped are crucial regulators of hedgehog niche expression and prohemocyte maintenance during Drosophila larval hematopoiesis. Development. 2010;137:3561-8 pubmed publisher
Plaza S, Prince F, Adachi Y, Punzo C, Cribbs D, Gehring W. Cross-regulatory protein-protein interactions between Hox and Pax transcription factors. Proc Natl Acad Sci U S A. 2008;105:13439-44 pubmed publisher
Prince F, Katsuyama T, Oshima Y, Plaza S, Resendez Perez D, Berry M, et al. The YPWM motif links Antennapedia to the basal transcriptional machinery. Development. 2008;135:1669-79 pubmed publisher
Miguel Aliaga I, Thor S, Gould A. Postmitotic specification of Drosophila insulinergic neurons from pioneer neurons. PLoS Biol. 2008;6:e58 pubmed publisher
Diop S, Bertaux K, Vasanthi D, Sarkeshik A, Goirand B, Aragnol D, et al. Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control. EMBO Rep. 2008;9:260-6 pubmed publisher
Dos Santos N, Rubin T, Chalvet F, Gandille P, Cremazy F, Leroy J, et al. Drosophila retinal pigment cell death is regulated in a position-dependent manner by a cell memory gene. Int J Dev Biol. 2008;52:21-31 pubmed
Merabet S, Saadaoui M, Sambrani N, Hudry B, Pradel J, Affolter M, et al. A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax. Proc Natl Acad Sci U S A. 2007;104:16946-51 pubmed
Halachmi N, Schulze K, Inbal A, Salzberg A. Additional sex combs affects antennal development by means of spatially restricted repression of Antp and wg. Dev Dyn. 2007;236:2118-30 pubmed
Parrish J, Emoto K, Jan L, Jan Y. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev. 2007;21:956-72 pubmed
Miguel Aliaga I, Thor S. Segment-specific prevention of pioneer neuron apoptosis by cell-autonomous, postmitotic Hox gene activity. Development. 2004;131:6093-105 pubmed
Shiga Y, Yasumoto R, Yamagata H, Hayashi S. Evolving role of Antennapedia protein in arthropod limb patterning. Development. 2002;129:3555-61 pubmed
Johnston L, Ostrow B, Jasoni C, Blochlinger K. The homeobox gene cut interacts genetically with the homeotic genes proboscipedia and Antennapedia. Genetics. 1998;149:131-42 pubmed
Hayward D, Patel N, Rehm E, Goodman C, Ball E. Sequence and expression of grasshopper antennapedia: comparison to Drosophila. Dev Biol. 1995;172:452-65 pubmed publisher
Zeng W, Andrew D, Mathies L, Horner M, Scott M. Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity. Development. 1993;118:339-52 pubmed
Stuart J, Brown S, Beeman R, Denell R. The Tribolium homeotic gene Abdominal is homologous to abdominal-A of the Drosophila bithorax complex. Development. 1993;117:233-43 pubmed
Breen T, Harte P. Trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development. 1993;117:119-34 pubmed
Cimbora D, Sakonju S. Drosophila midgut morphogenesis requires the function of the segmentation gene odd-paired. Dev Biol. 1995;169:580-95 pubmed
Glicksman M, Brower D. Misregulation of homeotic gene expression in Drosophila larvae resulting from mutations at the extra sex combs locus. Dev Biol. 1988;126:219-27 pubmed
Reuter R, Panganiban G, Hoffmann F, Scott M. Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development. 1990;110:1031-40 pubmed
Glicksman M, Brower D. Persistent ectopic expression of Drosophila homeotic genes resulting from maternal deficiency of the extra sex combs gene product. Dev Biol. 1990;142:422-31 pubmed
Reuter R, Scott M. Expression and function of the homoeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development. 1990;109:289-303 pubmed
product information
Internal ID :
1352
Name :
anti-Antp 4C3
Depositor Name :
Brower, D.
Depositor Institution :
University of Arizona
Date Deposited :
7/17/02
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Antennapedia protein
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Beetle,Broad species,Drosophila,Grasshopper
Species Tested (legacy) :
broad species binding
Initial Publication Pubmed ID :
22
Depositor Notes (Special Instructions) :
Species Specificity: shows broad species binding.
Collections :
Cardiac development,Drosophila antigens,Transcription factors
Search Keywords :
Brower, Danny, Antennapedia protein, Drosophila, MIgG1, Broad species/Drosophila/Grasshopper/Beetle, Antp, AntP; ANTP; AntP1;Dmel CG1028; , AB_528082, monoclonal
Antigen Molecular Weight :
Predicted: 43kDa (multiple isoforms from 33 to 43kDa)
Gene :
Antp
Alternate Gene Name(s) :
AntP; ANTP; AntP1;Dmel CG1028;
Uniprot ID :
P02833
Antibody Registry ID :
AB_528082
Immunogen :
lacZ-Antp fusion protein
Clonality :
Monoclonal
Myeloma Strain :
NSO
Epitope Mapped :
No
Recommended Applications :
Gel Supershift,Immunofluorescence,Immunohistochemistry
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
18259215 7781900 7900986 8612963 2895027 1976087 7900984 1979545 7900989
Immunofluorescence Pubmed IDs :
18259215 23919509 9584091 20876645 25280996 22110713 17942685 15537690 22911822 17654717 22916033 18755899 25169193 22046139 22393361 24803653 2895027 1979545
Western Blot Pubmed IDs :
18367556
Gel Supershift Pubmed IDs :
24333180
Pubmed IDs :
18336071 18033669 17437999 12117806 1983113
Depositor Growth Medium :
RPMI
DSHB Growth Medium :
RPMI
References (legacy) :
Drosophila Info. Serv. 70, 52-54.; Dev. Biol. 352, 308-316.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US