product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Tyrosine hydroxylase (Tyrosine 3-monooxygenase)
catalog :
aTH
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
aTH
reactivity :
Japanese quail
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 12
Reference |
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Lacosta A, Muniesa P, Ruberte J, Sarasa M, Dominguez L. Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos. Pigment Cell Res. 2005;18:243-51 pubmed
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Lee V, Bronner Fraser M, Baker C. Restricted response of mesencephalic neural crest to sympathetic differentiation signals in the trunk. Dev Biol. 2005;278:175-92 pubmed
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Ziller C, Mirabel M, Vandenbunder B, Fauquet M. The tyrosine hydroxylase gene is expressed in endoderm and pancreas of early quail embryos. Anat Embryol (Berl). 1994;189:307-15 pubmed
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Selleck M, Bronner Fraser M. Origins of the avian neural crest: the role of neural plate-epidermal interactions. Development. 1995;121:525-38 pubmed
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Fauquet M, Ziller C. A monoclonal antibody directed against quail tyrosine hydroxylase: description and use in immunocytochemical studies on differentiating neural crest cells. J Histochem Cytochem. 1989;37:1197-205 pubmed
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Garcia Arraras J, Lugo Chinchilla A, Chévere Colón I. The expression of neuropeptide Y immunoreactivity in the avian sympathoadrenal system conforms with two models of coexpression development for neurons and chromaffin cells. Development. 1992;115:617-27 pubmed
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Nataf V, Monier S. Effect of insulin and insulin-like growth factor I on the expression of the catecholaminergic phenotype by neural crest cells. Brain Res Dev Brain Res. 1992;69:59-66 pubmed
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product information
Internal ID :
2964
Name :
aTH
Depositor Name :
Le Douarin, N. / Ziller, C.
Depositor Institution :
Institut d’Embryologie Cellulaire et Moleculaire du C.N.R.S. et du College de France, Nogent sur Marne
Date Deposited :
8/13/92
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Tyrosine hydroxylase (Tyrosine 3-monooxygenase)
Antigen Species :
Quail
Host Species :
mouse
Isotype :
MIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Chicken,Cuttlefish,Quail
Species Tested (legacy) :
chick & quail
Initial Publication Pubmed ID :
2569003
Depositor Notes (Special Instructions) :
This antibody gives an intracytoplasmic staining of dopaminergic neurons.
Collections :
Enzymes,Neurodevelopment
Search Keywords :
Le Douarin, N. / Ziller, C., Tyrosine hydroxylase (Tyrosine 3-monooxygenase), Quail, MIgG2a, Quail/Chicken/Cuttlefish, TH, , AB_528490, monoclonal, Enzymes/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Western blot
Antigen Molecular Weight :
Predicted: 56 kDa; Apparent: 63 kDa
Gene :
TH
Uniprot ID :
P11982
Antibody Registry ID :
AB_528490
Synonyms (Alternate Clone Names) :
alphaQTOH
Immunogen :
Recombinant TH (aa 60-368)/beta galactosidase fusion protein
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
SP2/0
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 60-368
Epitope Map PubMed ID :
2569003
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Western Blot
Immunohistochemistry Pubmed IDs :
2569003 19795495
Immunofluorescence Pubmed IDs :
2569003 15649470 21199918 7768190 7915502 1358479 1358595 26053997
Western Blot Pubmed IDs :
2569003 21199918 19795495
Pubmed IDs :
16029418
Additional Information :
This protein is involved in the synthesis of dopamine from L-tyrosine.
DSHB Growth Medium :
Iscove's
References (legacy) :
J. Histochem. Cytochem. 37, 1197-1205.; Development 121, 525-538.; Pigment Cell Res. 18(4), 243-251.
more info or order :
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Developmental Studies Hybridoma Bank
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