product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Ultrabithorax 5' exon (107 amino acids)
catalog :
Ubx FP3.38
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ubx FP3.38
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; fruit fly; 1:50; loading ...; fig 2b
Zmojdzian M, de Joussineau S, Da Ponte J, Jagla K. Distinct subsets of Eve-positive pericardial cells stabilise cardiac outflow and contribute to Hox gene-triggered heart morphogenesis in Drosophila. Development. 2018;145: pubmed publisher
  • immunohistochemistry; fruit fly; 1:20; loading ...; fig 1A
Hessinger C, Technau G, Rogulja Ortmann A. The Drosophila Hox gene Ultrabithorax acts in both muscles and motoneurons to orchestrate formation of specific neuromuscular connections. Development. 2017;144:139-150 pubmed publisher
  • immunohistochemistry; fruit fly; 1:20
Moris Sanz M, Estacio Gómez A, Sánchez Herrero E, Díaz Benjumea F. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015;4:1132-42 pubmed publisher
Alvarez Rivero J, Moris Sanz M, Estacio Gómez A, Montoliu Nerin M, Diaz Benjumea F, Herrero P. Variability in the number of abdominal leucokinergic neurons in adult Drosophila melanogaster. J Comp Neurol. 2017;525:639-660 pubmed publisher
Sadasivam D, Huang D. Maintenance of Tissue Pluripotency by Epigenetic Factors Acting at Multiple Levels. PLoS Genet. 2016;12:e1005897 pubmed publisher
Savitsky M, Kim M, Kravchuk O, Schwartz Y. Distinct Roles of Chromatin Insulator Proteins in Control of the Drosophila Bithorax Complex. Genetics. 2016;202:601-17 pubmed publisher
Geyer A, Koltsaki I, Hessinger C, Renner S, Rogulja Ortmann A. Impact of Ultrabithorax alternative splicing on Drosophila embryonic nervous system development. Mech Dev. 2015;138 Pt 2:177-189 pubmed publisher
Bivik C, Bahrampour S, Ulvklo C, Nilsson P, Angel A, Fransson F, et al. Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells. Genetics. 2015;200:1229-44 pubmed publisher
Blanch M, Piñeyro D, Bernués J. New insights for Drosophila GAGA factor in larvae. R Soc Open Sci. 2015;2:150011 pubmed publisher
Dupont C, Dardalhon Cuménal D, Kyba M, Brock H, Randsholt N, Peronnet F. Drosophila Cyclin G and epigenetic maintenance of gene expression during development. Epigenetics Chromatin. 2015;8:18 pubmed publisher
Baëza M, Viala S, Heim M, Dard A, Hudry B, Duffraisse M, et al. Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo. elife. 2015;4: pubmed publisher
Foos N, Maurel Zaffran C, Maté M, Vincentelli R, Hainaut M, Bérenger H, et al. A flexible extension of the Drosophila ultrabithorax homeodomain defines a novel Hox/PBC interaction mode. Structure. 2015;23:270-9 pubmed publisher
Patterson J, Arenas Gamboa A, Wang T, Hsiao H, Howell D, Pellois J, et al. Materials composed of the Drosophila Hox protein Ultrabithorax are biocompatible and nonimmunogenic. J Biomed Mater Res A. 2015;103:1546-53 pubmed publisher
Alfieri C, Gambetta M, Matos R, Glatt S, Sehr P, Fraterman S, et al. Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements. Genes Dev. 2013;27:2367-79 pubmed publisher
Pavlopoulos A, Akam M. Hox gene Ultrabithorax regulates distinct sets of target genes at successive stages of Drosophila haltere morphogenesis. Proc Natl Acad Sci U S A. 2011;108:2855-60 pubmed publisher
Tour E, Hittinger C, McGinnis W. Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax. Development. 2005;132:5271-81 pubmed
Stern D. A role of Ultrabithorax in morphological differences between Drosophila species. Nature. 1998;396:463-6 pubmed
White R, Wilcox M. Protein products of the bithorax complex in Drosophila. Cell. 1984;39:163-71 pubmed
Gavis E, Hogness D. Phosphorylation, expression and function of the Ultrabithorax protein family in Drosophila melanogaster. Development. 1991;112:1077-93 pubmed
Graba Y, Aragnol D, Laurenti P, Garzino V, Charmot D, Berenger H, et al. Homeotic control in Drosophila; the scabrous gene is an in vivo target of Ultrabithorax proteins. EMBO J. 1992;11:3375-84 pubmed
product information
Internal ID :
6598
Name :
Ubx FP3.38
Depositor Name :
White, R.
Depositor Institution :
University of Cambridge
Date Deposited :
5/25/10
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Ultrabithorax 5' exon (107 amino acids)
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila melanogaster,Drosophila simulans
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
6091908
Depositor Notes (Special Instructions) :
Limited species specificity
Collections :
Cell adhesion,Cytoskeleton,Drosophila antigens,Nucleus,Transcription factors
Search Keywords :
White, R., Ultrabithorax 5' exon (107 amino acids), Drosophila, MIgG1, Drosophila melanogaster/Drosophila simulans, Ubx, CG10388, bx, Cbx, pbx, abx, bxd, DmUbx, AB_10805300, monoclonal, Drosophila antigens/Cytoskeletal elements/cell adhesion/Transcription factors/Nucleus, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation/Chromatin Immunoprecipitation
Antigen Molecular Weight :
Predicted: multiple isoforms, from 35 to 40kDa
Gene :
Ubx
Alternate Gene Name(s) :
CG10388, bx, Cbx, pbx, abx, bxd, DmUbx
Uniprot ID :
P83949
Antibody Registry ID :
AB_10805300
Synonyms (Alternate Clone Names) :
FP3.38
Immunogen :
Recombinant Drosophila Ultrabithorax 5’ exon (107 aa)/lacZ fusion protein
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
NSO
Epitope Mapped :
Yes
Epitope Location or Sequence :
N-terminal region encoded by the 5' exon (aa 1-107)
Epitope Map PubMed ID :
6091908
Recommended Applications :
Chromatin Immunoprecipitation,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
25995770 31327720 31327720
Immunofluorescence Pubmed IDs :
6091908 25651060 26299253 26715665 27506156 26064623 26926299 25869471 16284118 21282633 24186981 9853753
Western Blot Pubmed IDs :
6091908 25087647 26299253 1682129 1505521
Chromatin Immunoprecipitation Pubmed IDs :
1505521
Additional Information :
The N-terminal region containing the epitope recognized by Ubx FP3.38 is common to all isoforms
DSHB Growth Medium :
RPMI
References (legacy) :
Cell 39, 163-171.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US