product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Talin carboxy terminus 534 amino acids
catalog :
Talin A22A
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Talin A22A
reactivity :
fruit fly
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 3
Reference
Meehan T, Kleinsorge S, Timmons A, Taylor J, McCall K. Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary. Dis Model Mech. 2015;8:1603-14 pubmed publisher
Schardt L, Ander J, Lohmann I, Papagiannouli F. Stage-specific control of niche positioning and integrity in the Drosophila testis. Mech Dev. 2015;138 Pt 3:336-48 pubmed publisher
Brown N, Gregory S, Rickoll W, Fessler L, Prout M, White R, et al. Talin is essential for integrin function in Drosophila. Dev Cell. 2002;3:569-79 pubmed
product information
Internal ID :
6588
Name :
Talin A22A
Depositor Name :
White, R.
Depositor Institution :
University of Cambridge
Date Deposited :
5/25/10
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Talin carboxy terminus 534 amino acids
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
12408808
Depositor Notes (Special Instructions) :
Recommend use as a cocktail of monoclonal antibodies (A22A plus E16B) for immunohistochemistry.
Collections :
Cell adhesion,Cytoskeleton,Drosophila antigens
Search Keywords :
White, R., Talin carboxy terminus 534 amino acids, Drosophila, MIgG1, Drosophila, rhea, CG6831, tendrils, Tln, talin, AB_10660289, monoclonal, Cell adhesion/Cytoskeletal elements/Drosophila antigens, Immunofluorescence/Western blot/Immunoprecipitation
Antigen Molecular Weight :
Multiple isoforms; Predicted (isoform B): 307 kDa
Gene :
rhea
Alternate Gene Name(s) :
CG6831, tendrils, Tln, talin
Uniprot ID :
Q9VSL8
Antibody Registry ID :
AB_10660289
Immunogen :
Recombinant talin, C-terminal (534 amino acids of isoform B)/GST fusion protein
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
NSO
Epitope Mapped :
Yes
Epitope Location or Sequence :
C-terminal (aa 2302-2836) of isoform B
Epitope Map PubMed ID :
12408808
Recommended Applications :
Immunofluorescence,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
yes
Immunofluorescence Pubmed IDs :
12408808 26226434 26398951 29738712
Western Blot Pubmed IDs :
12408808
Additional Information :
This antibody should recognize isoforms B and G and may recognize isoform H, but will not recognize isoforms C or I.
DSHB Growth Medium :
RPMI
References (legacy) :
Dev. Cell. 3, 569-579
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US