Jagged 1 protein | Developmental Studies Hybridoma Bank TS1.15H product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Jagged 1 protein

catalog :

TS1.15H

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

TS1.15H

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - frozen section

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 6h	Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, et al. Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021;148: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 2k	Zhang H, Xie J, So K, Tong K, Sae Pang J, Wang L, et al. Hoxb3 Regulates Jag1 Expression in Pharyngeal Epithelium and Affects Interaction With Neural Crest Cells. Front Physiol. 2020;11:612230 pubmed publisher
immunohistochemistry; mouse; 1:300; loading ...; fig 3b	Wang L, Xie J, Zhang H, Tsang L, Tsang S, Braune E, et al. Notch signalling regulates epibranchial placode patterning and segregation. Development. 2020;147: pubmed publisher
immunohistochemistry; mouse; 1:50; fig 2c	Reinhardt R, Gullotta F, Nusspaumer G, Unal E, Ivanek R, Zuniga A, et al. Molecular signatures identify immature mesenchymal progenitors in early mouse limb buds that respond differentially to morphogen signaling. Development. 2019;146: pubmed publisher
	Yu J, Canalis E. The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α. J Biol Chem. 2019;294:14203-14214 pubmed publisher
	Zhang H, Wang L, Wong E, Tsang S, Xu P, Lendahl U, et al. An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis. elife. 2017;6: pubmed publisher
	Brunskill E, Park J, Chung E, Chen F, Magella B, Potter S. Single cell dissection of early kidney development: multilineage priming. Development. 2014;141:3093-101 pubmed publisher
	Del Papa B, Sportoletti P, Cecchini D, Rosati E, Balucani C, Baldoni S, et al. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction. Eur J Immunol. 2013;43:182-7 pubmed publisher
	Park J, Ma W, O Brien L, Chung E, Guo J, Cheng J, et al. Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Dev Cell. 2012;23:637-51 pubmed publisher
	Rosati E, Sabatini R, Rampino G, Tabilio A, Di Ianni M, Fettucciari K, et al. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells. Blood. 2009;113:856-65 pubmed publisher
	Curry C, Reed L, Nickoloff B, Miele L, Foreman K. Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Lab Invest. 2006;86:842-52 pubmed
	Cuevas I, Slocum A, Jun P, Costello J, Bollen A, Riggins G, et al. Meningioma transcript profiles reveal deregulated Notch signaling pathway. Cancer Res. 2005;65:5070-5 pubmed
	Jundt F, Anagnostopoulos I, Forster R, Mathas S, Stein H, Dorken B. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood. 2002;99:3398-403 pubmed
	Gray G, Mann R, Mitsiadis E, Henrique D, Carcangiu M, Banks A, et al. Human ligands of the Notch receptor. Am J Pathol. 1999;154:785-94 pubmed

product information

Internal ID :

439

Name :

TS1.15H

Depositor Name :

Artavanis-Tsakonas, S.

Depositor Institution :

Harvard Medical School

Depositor Website :

https://artavanis-tsakonas.hms.harvard.edu/

Date Deposited :

5/2/00

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Jagged 1 protein

Antigen Species :

Human

Host Species :

rat

Isotype :

MIgG2a

Isotype for catalog (legacy) :

IgG2a

Positive Tested Species Reactivity :

Human

Species Tested (legacy) :

human

Initial Publication Pubmed ID :

10079256

Collections :

CD antigens,Cell signaling,Human

Search Keywords :

Artavanis-Tsakonas, S., Jagged 1 protein, Human, MIgG2a, Human, JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1, AB_528317, Monoclonal , Human/CD antigens, Western blot/Immunohistochemistry

Antigen Molecular Weight :

134 kDa

Gene :

JAG1

Alternate Gene Name(s) :

AGS, AHD, AWS, CD339, HJ1, JAGL1

Uniprot ID :

P78504

Antibody Registry ID :

AB_528317

Immunogen :

Intracellular domain-GST fusion protein

Immunogen Sequence :

Protein domain

Clonality :

Monoclonal

Myeloma Strain :

Ag8 cells

Epitope Mapped :

Epitope Location or Sequence :

Intracellular domain of human jagged1

Recommended Applications :

Immunohistochemistry,Western Blot

Immunoblotting (legacy) :

Good

Immunohistochemistry Pubmed IDs :

10079256 11964309 29140246

Immunofluorescence Pubmed IDs :

10079256 22902740 25053437

Western Blot Pubmed IDs :

10079256 18796623 16732296 15958550 23161436 31371452

FFPE Pubmed IDs :

10079256

Additional Information :

RRID:AB_528317

DSHB Growth Medium :

RPMI

References (legacy) :

Am. J. Pathol. 154(3), 785-794.; Dev. Cell 23, 637-651.

more info or order :

Developmental Studies Hybridoma Bank product webpage