| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; 1:10; loading ...; fig s9d
| Hu S, Liu S, Bian Y, Poddar M, Singh S, Cao C, et al. Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b. Cell Rep Med. 2022;3:100754 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 4b
| Mancinelli R, Ceci L, Kennedy L, Francis H, Meadows V, Chen L, et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells. 2022;11: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2f
| Liu Y, Deguchi Y, Wei D, Liu F, Moussalli M, Deguchi E, et al. Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ. Nat Commun. 2022;13:2665 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
| Kidger A, Saville M, Rushworth L, Davidson J, Stellzig J, Ono M, et al. Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6. Oncogene. 2022;41:2811-2823 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1b
- immunocytochemistry; mouse; fig 2h
| Pantasis S, Friemel J, Brütsch S, Hu Z, Krautbauer S, Liebisch G, et al. Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation. J Cell Sci. 2022;135: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1j
| Molina L, Zhu J, Li Q, Pradhan Sundd T, Krutsenko Y, Sayed K, et al. Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021;36:109310 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 4g
| Pocaterra A, Scattolin G, Romani P, Ament C, Ribback S, Chen X, et al. Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development. Commun Biol. 2021;4:763 pubmed publisher |
- immunocytochemistry; mouse; fig 7d
- immunohistochemistry; mouse; 1:100; fig 6i
| Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1b
| Flowers B, Xu H, Mulligan A, Hanson K, Seoane J, Vogel H, et al. Cell of Origin Influences Pancreatic Cancer Subtype. Cancer Discov. 2021;11:660-677 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 5f
- immunohistochemistry; mouse; loading ...; fig 5f
| Hendley A, Rao A, Leonhardt L, Ashe S, Smith J, Giacometti S, et al. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. elife. 2021;10: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 1f
| Hsieh M, Weng C, Lin Y, Wu C, Chen L, Cheng K. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice. Int J Mol Sci. 2021;22: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s5
- western blot; mouse; fig 4c
| Krausová A, Buresova P, Sarnova L, Oyman Eyrilmez G, Skarda J, Wohl P, et al. Plectin ensures intestinal epithelial integrity and protects colon against colitis. Mucosal Immunol. 2021;14:691-702 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2b
| Hankeova S, Salplachta J, Zikmund T, Kavkova M, Van Hul N, Brinek A, et al. DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome. elife. 2021;10: pubmed publisher |
- immunohistochemistry - frozen section; human; 1:100; loading ...; fig s12b
- immunocytochemistry; human; 1:100; loading ...; fig 1c
| Sampaziotis F, Muraro D, Tysoe O, Sawiak S, Beach T, Godfrey E, et al. Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science. 2021;371:839-846 pubmed publisher |
- immunocytochemistry; mouse; 1:200; loading ...; fig s3d
| Prior N, Hindley C, Rost F, Meléndez E, Lau W, Gottgens B, et al. Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool. Development. 2019;146: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 1d
- western blot; mouse; loading ...; fig 4c
| Krishna Subramanian S, Singer S, Armaka M, Banales J, Hölzer K, Schirmacher P, et al. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019;: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:3; loading ...; fig 5c
| Gorth D, Shapiro I, Risbud M. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis. 2018;10:7 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 3b
| He P, Yang J, Yang V, Bialkowska A. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018;154:1494-1508.e13 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1d
| Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s2b
| Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 1b
| Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al. NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma. J Exp Med. 2017;214:1711-1724 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1d
| Halbrook C, Wen H, Ruggeri J, Takeuchi K, Zhang Y, di Magliano M, et al. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cell Mol Gastroenterol Hepatol. 2017;3:99-118 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1d
| Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016;7:13369 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 1b
| Li Q, Wang H, Zogopoulos G, Shao Q, Dong K, Lv F, et al. Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:77838-77853 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 3d
| Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 1
| Hintermann E, Bayer M, Ehser J, Aurrand Lions M, Pfeilschifter J, Imhof B, et al. Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis. Cell Adh Migr. 2016;10:419-33 pubmed publisher |
- immunocytochemistry; mouse; 1:10; fig 4
| Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s2c
| Seifert L, Werba G, Tiwari S, Giao Ly N, Nguy S, Alothman S, et al. Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice. Gastroenterology. 2016;150:1659-1672.e5 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; fig s2
| Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke J, et al. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. 2016;35:3880-6 pubmed publisher |
- immunocytochemistry; mouse; fig 2
| Pajoohesh Ganji A, Pal Ghosh S, Tadvalkar G, Stepp M. K14 + compound niches are present on the mouse cornea early after birth and expand after debridement wounds. Dev Dyn. 2016;245:132-43 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 4
- immunohistochemistry - paraffin section; human; fig 4
| Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500; fig s5e
| Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 1
| Chiou S, Winters I, Wang J, Naranjo S, Dudgeon C, Tamburini F, et al. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev. 2015;29:1576-85 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 2
| Li X, Tao J, Cigliano A, Sini M, Calderaro J, Azoulay D, et al. Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver. Oncotarget. 2015;6:10102-15 pubmed |
- immunocytochemistry; human; 1:20
| Lee J, Garbe J, Vrba L, Miyano M, Futscher B, Stampfer M, et al. Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells. Front Cell Dev Biol. 2015;3:13 pubmed publisher |
- western blot; mouse; 1:500; fig s3
| Wögenstein K, Szabo S, Lunova M, Wiche G, Haybaeck J, Strnad P, et al. Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. PLoS ONE. 2014;9:e108323 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; fig 2
| Morris S, Carter K, Baek J, Koszarek A, Yeh M, Knoblaugh S, et al. TGF-? signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene. 2015;34:3273-82 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig s2
| Ehlken H, Krishna Subramanian S, Ochoa Callejero L, Kondylis V, Nadi N, Straub B, et al. Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout. Cell Death Differ. 2014;21:1721-32 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400; fig 7
| Karaca G, Swiderska Syn M, Xie G, Syn W, Krüger L, Machado M, et al. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. PLoS ONE. 2014;9:e83987 pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:750
| Chan I, Guy C, Machado M, Wank A, Kadiyala V, Michelotti G, et al. Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis. Alcohol Clin Exp Res. 2014;38:787-800 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Reichert M, Takano S, von Burstin J, Kim S, Lee J, Ihida Stansbury K, et al. The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Genes Dev. 2013;27:288-300 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200
| Carrasco M, Delgado I, Soria B, Martin F, Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 2012;122:3504-15 pubmed publisher |
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| Yamaguchi T, Ikehara S, Akimoto Y, Nakanishi H, Kume M, Yamamoto K, et al. TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma. Sci Rep. 2019;9:11247 pubmed publisher |
| Liu Y, Kim H, Dong E, Dong C, Huang M, Liu Y, et al. Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:2685-2693 pubmed publisher |
| Mohanty S, Pinelli R, Pricop P, Albert T, Dahia C. Chondrocyte-like nested cells in the aged intervertebral disc are late-stage nucleus pulposus cells. Aging Cell. 2019;18:e13006 pubmed publisher |
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| Pocaterra A, Santinon G, Romani P, Brian I, Dimitracopoulos A, Ghisleni A, et al. F-actin dynamics regulates mammalian organ growth and cell fate maintenance. J Hepatol. 2019;71:130-142 pubmed publisher |
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| Rubio Tomás T, Aguilar Bravo B, Sancho Bru P. Genetic Lineage Tracing of Biliary Epithelial Cells. Methods Mol Biol. 2019;1905:45-57 pubmed publisher |
| Goehrig D, Nigri J, Samain R, Wu Z, Cappello P, Gabiane G, et al. Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer. Gut. 2019;68:693-707 pubmed publisher |
| Zhang R, Zeng X, Lin Z, Ming Fu -, Tong Y, Lui V, et al. Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure. World J Gastroenterol. 2018;24:3260-3272 pubmed publisher |
| Livshits G, Alonso Curbelo D, Morris J, Koche R, Saborowski M, Wilkinson J, et al. Arid1a restrains Kras-dependent changes in acinar cell identity. elife. 2018;7: pubmed publisher |
| Zubeldia Plazaola A, Recalde Percaz L, Moragas N, Alcaraz M, Chen X, Mancino M, et al. Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis. Breast Cancer Res. 2018;20:65 pubmed publisher |
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| Silagi E, Batista P, Shapiro I, Risbud M. Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. Sci Rep. 2018;8:4856 pubmed publisher |
| Hernandez C, Huebener P, Pradere J, Antoine D, Friedman R, Schwabe R. HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest. 2018;128:2436-2451 pubmed publisher |
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| Gonzalez Rodriguez A, Valdecantos M, Rada P, Addante A, Barahona I, Rey E, et al. Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis. Mol Metab. 2018;7:132-146 pubmed publisher |
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