product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
troponin I, cardiac and slow-twitch skeletal
catalog :
TI-4
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TI-4
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 15
Reference
Hall D, Ponce J, Chen B, Spitler K, Alexia A, Oudit G, et al. Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure. JCI Insight. 2017;2: pubmed publisher
Liu S, Navaei A, Meng X, Nikkhah M, Chae J. Wireless Passive Stimulation of Engineered Cardiac Tissues. ACS Sens. 2017;2:1006-1012 pubmed publisher
Navaei A, Saini H, Christenson W, Sullivan R, Ros R, Nikkhah M. Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs. Acta Biomater. 2016;41:133-46 pubmed publisher
Chan S, Hagen H, Swanson S, Stewart R, Boll K, Aho J, et al. Development of Bipotent Cardiac/Skeletal Myogenic Progenitors from MESP1+ Mesoderm. Stem Cell Reports. 2016;6:26-34 pubmed publisher
Navaei A, Truong D, Heffernan J, Cutts J, Brafman D, Sirianni R, et al. PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering. Acta Biomater. 2016;32:10-23 pubmed publisher
Saini H, Navaei A, Van Putten A, Nikkhah M. 3D cardiac microtissues encapsulated with the co-culture of cardiomyocytes and cardiac fibroblasts. Adv Healthc Mater. 2015;4:1961-71 pubmed publisher
Mastrototaro G, Liang X, Li X, Carullo P, Piroddi N, Tesi C, et al. Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers. Cardiovasc Res. 2015;107:216-25 pubmed publisher
Bicer S, Reiser P. Complex tropomyosin and troponin T isoform expression patterns in orbital and global fibers of adult dog and rat extraocular muscles. J Muscle Res Cell Motil. 2013;34:211-31 pubmed publisher
Schiaffino S, Gorza L, Ausoni S. Troponin isoform switching in the developing heart and its functional consequences. Trends Cardiovasc Med. 1993;3:12-7 pubmed publisher
Thijssen V, Ausma J, Gorza L, van der Velden H, Allessie M, Van Gelder I, et al. Troponin I isoform expression in human and experimental atrial fibrillation. Circulation. 2004;110:770-5 pubmed
Westfall M, Albayya F, Metzger J. Functional analysis of troponin I regulatory domains in the intact myofilament of adult single cardiac myocytes. J Biol Chem. 1999;274:22508-16 pubmed
Westfall M, Rust E, Metzger J. Slow skeletal troponin I gene transfer, expression, and myofilament incorporation enhances adult cardiac myocyte contractile function. Proc Natl Acad Sci U S A. 1997;94:5444-9 pubmed
Westfall M, Samuelson L, Metzger J. Troponin I isoform expression is developmentally regulated in differentiating embryonic stem cell-derived cardiac myocytes. Dev Dyn. 1996;206:24-38 pubmed
Gorza L, Ausoni S, Merciai N, Hastings K, Schiaffino S. Regional differences in troponin I isoform switching during rat heart development. Dev Biol. 1993;156:253-64 pubmed
Saggin L, Gorza L, Ausoni S, Schiaffino S. Troponin I switching in the developing heart. J Biol Chem. 1989;264:16299-302 pubmed
product information
Internal ID :
6188
Name :
TI-4
Depositor Name :
Schiaffino, S.
Depositor Institution :
Universita degli Studi di Padova,Padova, Italy
Date Deposited :
3/15/09
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
troponin I, cardiac and slow-twitch skeletal
Antigen Species :
Bovine
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Canine,Goat,Human,Mouse,Rat
Species Tested (legacy) :
rat and mouse
Initial Publication Pubmed ID :
2777792
Collections :
Cardiac development,Human,Skeletal muscle
Search Keywords :
Schiaffino, S., troponin I, cardiac and slow-twitch skeletal, Bovine, MIgG1, Rat/Mouse/Dog/Goat/Human, TNNI3, AB_10573815, Monoclonal, Human/Cardiac development proteins/Skeletal muscle, Western blotting/Immunohistochemistry/Immunofluorescence
Antigen Molecular Weight :
24.0 kDa
Gene :
TNNI3
Uniprot ID :
P08057
Antibody Registry ID :
AB_10573815
Immunogen :
Purified troponin complex/adult bovine heart
Clonality :
Monoclonal
Myeloma Strain :
NS0
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
10428827 8449370
Immunofluorescence Pubmed IDs :
27212425 26129820 26689467 9144257 28750525 21244965 9019244 8449370 10428827 26771351
Western Blot Pubmed IDs :
25987543 23700265 9144257 9019244 8449370 10428827 15289369 26771351 28768905
DSHB Growth Medium :
Iscove's
References (legacy) :
J. Biol. Chem. 264(27), 16299-16303.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US