Tropomyosin alpha-3 chain isoform 5 splice variant TC22 | Developmental Studies Hybridoma Bank TC22-4 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Tropomyosin alpha-3 chain isoform 5 splice variant TC22

catalog :

TC22-4

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TC22-4

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 1

Reference
Lin J, Geng X, Bhattacharya S, Yu J, Reiter R, Sastri B, et al. Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer. Gastroenterology. 2002;123:152-62 pubmed

product information

Internal ID :

35138

Name :

TC22-4

Depositor Name :

Lin, J. J-C.

Depositor Institution :

University of Iowa

Date Deposited :

3/19/15

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Tropomyosin alpha-3 chain isoform 5 splice variant TC22

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Positive Tested Species Reactivity :

Human

Depositor Notes (Special Instructions) :

hTM5 isoform is expressed in normal colon epithelial. TC22 is an alternatively spliced variant of hTM5 with an altered C-terminal sequence (a.a. 222-247) that is strongly associated with colonic neoplasms and carcinoma.

Collections :

Cell markers,Cytoskeleton,Human

Search Keywords :

Lin, J. J-C., Tropomyosin alpha-3 chain isoform 5 splice variant TC22, Human, MIgG1, Human, TPM3, TM-5, , Monoclonal, Human/Cytoskeleton/Cell markers, Immunohistochemistry/Immunofluorescence/Western blot/ELISA/FACS/

Antigen Molecular Weight :

28.7 kDa

Gene :

TPM3

Alternate Gene Name(s) :

TM-5

Uniprot ID :

P06753-4

Immunogen :

Synthetic peptide a.a. 223-247

Immunogen Sequence :

RLYSQLERNRLLSNELKLTLHDLCD

Clonality :

Monoclonal

Myeloma Strain :

NS1

Epitope Mapped :

Yes

Epitope Location or Sequence :

C-terminal splice variant of TC22

Epitope Map PubMed ID :

12105844

Recommended Applications :

ELISA,FACS,Immunofluorescence,Immunohistochemistry,Western Blot

Immunohistochemistry Pubmed IDs :

20309934 18321787

Immunofluorescence Pubmed IDs :

19369484

Western Blot Pubmed IDs :

19369484

ELISA Pubmed IDs :

19369484

FACS Pubmed IDs :

19369484

Additional Information :

US Patents 7285630B2 (2010), RE43,472 E (2012) and 9238040B2 (2016).

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage