CNP / Rip antigen | Developmental Studies Hybridoma Bank Rip product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

CNP / Rip antigen

catalog :

Rip

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RIP

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 15

Reference
Rodrigues G, Gaj T, Adil M, Wahba J, Rao A, Lorbeer F, et al. Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System. Stem Cell Reports. 2017;8:1770-1783 pubmed publisher
Galderisi U, Peluso G, Di Bernardo G, Calarco A, D Apolito M, Petillo O, et al. Efficient cultivation of neural stem cells with controlled delivery of FGF-2. Stem Cell Res. 2013;10:85-94 pubmed publisher
Garbe D, Ring R. Investigating tonic Wnt signaling throughout the adult CNS and in the hippocampal neurogenic niche of BatGal and ins-TopGal mice. Cell Mol Neurobiol. 2012;32:1159-74 pubmed
Deverman B, Patterson P. Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. J Neurosci. 2012;32:2100-9 pubmed publisher
van Aalst J, Boselie T, Beuls E, Vles J, van Straaten H. Spinal congenital dermal sinus in a chick embryo model. Laboratory investigation. J Neurosurg Pediatr. 2009;3:24-8 pubmed publisher
Miotke J, MacLennan A, Meyer R. Immunohistochemical localization of CNTFRalpha in adult mouse retina and optic nerve following intraorbital nerve crush: evidence for the axonal loss of a trophic factor receptor after injury. J Comp Neurol. 2007;500:384-400 pubmed
Horky L, Galimi F, Gage F, Horner P. Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol. 2006;498:525-38 pubmed
Watanabe M, Sakurai Y, Ichinose T, Aikawa Y, Kotani M, Itoh K. Monoclonal antibody Rip specifically recognizes 2',3'-cyclic nucleotide 3'-phosphodiesterase in oligodendrocytes. J Neurosci Res. 2006;84:525-33 pubmed
Fusco F, Martorana A, Giampà C, De March Z, Vacca F, Tozzi A, et al. Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes. Neurosci Lett. 2004;365:137-42 pubmed
Young H, Black A. Adult stem cells. Anat Rec A Discov Mol Cell Evol Biol. 2004;276:75-102 pubmed
Song H, Stevens C, Gage F. Astroglia induce neurogenesis from adult neural stem cells. Nature. 2002;417:39-44 pubmed
Nicot A, Dicicco Bloom E. Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression. Proc Natl Acad Sci U S A. 2001;98:4758-63 pubmed
Whittemore S, Morassutti D, Walters W, Liu R, Magnuson D. Mitogen and substrate differentially affect the lineage restriction of adult rat subventricular zone neural precursor cell populations. Exp Cell Res. 1999;252:75-95 pubmed
Friedman B, Hockfield S, Black J, Woodruff K, Waxman S. In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia. 1989;2:380-90 pubmed
Jhaveri S, Erzurumlu R, Friedman B, Schneider G. Oligodendrocytes and myelin formation along the optic tract of the developing hamster: an immunohistochemical study using the Rip antibody. Glia. 1992;6:138-48 pubmed

product information

Internal ID :

4141

Name :

Rip

Depositor Name :

Hockfield, S.

Depositor Institution :

Yale University School of Medicine

Date Deposited :

2/7/96

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

CNP / Rip antigen

Antigen Species :

Rat

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Hamster,Mouse,Rat

Species Tested (legacy) :

rat, hamster

Initial Publication Pubmed ID :

2530173

Depositor Notes (Special Instructions) :

Rip stains oligodendrocytes from early in their differentiation into adulthood. Expression preceeds myelin proteins. Rip stains mature oligodendrocytes, their cytoplasmic processes, and myelin in the adult rat spinal cord and cerebellum

Collections :

Cell markers,Neurodevelopment

Search Keywords :

Hockfield, S., CNP / Rip antigen, Rat, MIgG1, kappa light chain, Rat/Hamster/Mouse, , , AB_531796, monoclonal, Neurodevelopment/Cell markers, Immunohistochemistry/Immunofluorescence/Western Blot

Antigen Molecular Weight :

Apparent: 23 and 160 kDa

Gene :

Cnp

Uniprot ID :

P13233

Antibody Registry ID :

AB_531796

Immunogen :

Olfactory bulb granule cell layer from P [postnatal day] 12 rats and white matter from adult rats homogenized in phosphate-buffered saline.

Clonality :

Monoclonal

Myeloma Strain :

NS-1

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

2530173 1398895 14699636

Immunofluorescence Pubmed IDs :

2530173 10502401 11986659 15245795 22323722 22491991 23142801 11296303 28552605 16786579

Western Blot Pubmed IDs :

2530173 16786579

Immunoprecipitation Pubmed IDs :

16786579

Additional Information :

Rip antigen has been identified as 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP). See PMID: 16786579.

DSHB Growth Medium :

Iscove's

References (legacy) :

Glia 2, 380-390.; Glia 6(2), 138-148.; Exp. Cell Res. 252, 75-95.; PNAS 98(8), 4758-4763.; Nature 417, 39-44.; Anat. Rec. 263, 350-360.; Curr. Top. Microbiol. Immunol. 280, 71-109.; Anat. Rec. Part A 276A, 75-102.; Neurosci. Lett. 365, 137-142.; J. Neurosurg. Pediatr. 3, 24-28.

more info or order :

Developmental Studies Hybridoma Bank product webpage