elav Drosophila protein; embryonic lethal abnormal vision | Developmental Studies Hybridoma Bank Rat-Elav-7E8A10 anti-elav product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

elav Drosophila protein; embryonic lethal abnormal vision

catalog :

Rat-Elav-7E8A10 anti-elav

clonality :

monoclonal

host :

brown rat

conjugate :

nonconjugated

clone name :

Rat-Elav-7E8A10 anti-elav

reactivity :

Drosophila melanogaster

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 49

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; Drosophila melanogaster; 1:10; loading ...; fig 1e	Menon K, Kulkarni V, Takemura S, Anaya M, Zinn K. Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits. elife. 2019;8: pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:400; loading ...; fig 5s1a	Peng J, Lin S, Liu Y, Lin H, Li T, Yao C. A circuit-dependent ROS feedback loop mediates glutamate excitotoxicity to sculpt the Drosophila motor system. elife. 2019;8: pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:100; loading ...; fig 3c	Hakes A, Otsuki L, Brand A. A newly discovered neural stem cell population is generated by the optic lobe neuroepithelium during embryogenesis in Drosophila melanogaster. Development. 2018;145: pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:100; fig S17A"	Chen J, Reiher W, Hermann Luibl C, Sellami A, Cognigni P, Kondo S, et al. Allatostatin A Signalling in Drosophila Regulates Feeding and Sleep and Is Modulated by PDF. PLoS Genet. 2016;12:e1006346 pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:500; fig 1	Chen K, Lin G, Haelterman N, Ho T, Li T, Li Z, et al. Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. elife. 2016;5: pubmed publisher
immunohistochemistry - frozen section; Drosophila melanogaster; 1:1000; fig 2	Li T, Giagtzoglou N, Eberl D, Jaiswal S, Cai T, Godt D, et al. The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. elife. 2016;5: pubmed publisher
immunocytochemistry; Drosophila melanogaster; 1:100; fig 5	Le T, Vuong L, Kim A, Hsu Y, Choi K. 14-3-3 proteins regulate Tctp-Rheb interaction for organ growth in Drosophila. Nat Commun. 2016;7:11501 pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:200; fig 3C	Lee S, Bang S, Hong Y, Lee J, Jeong H, Park S, et al. The calcineurin inhibitor Sarah (Nebula) exacerbates AÎ²42 phenotypes in a Drosophila model of Alzheimer's disease. Dis Model Mech. 2016;9:295-306 pubmed publisher
immunohistochemistry - paraffin section; Drosophila melanogaster; 1:100; fig s6c	Gogendeau D, Siudeja K, Gambarotto D, Pennetier C, Bardin A, Basto R. Aneuploidy causes premature differentiation of neural and intestinal stem cells. Nat Commun. 2015;6:8894 pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:200; fig 2d	Gresser A, Gutzwiller L, Gauck M, Hartenstein V, Cook T, Gebelein B. Rhomboid Enhancer Activity Defines a Subset of Drosophila Neural Precursors Required for Proper Feeding, Growth and Viability. PLoS ONE. 2015;10:e0134915 pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:50	Okumura M, Sakuma C, Miura M, Chihara T. Linking cell surface receptors to microtubules: tubulin folding cofactor D mediates Dscam functions during neuronal morphogenesis. J Neurosci. 2015;35:1979-90 pubmed publisher
immunohistochemistry; Drosophila melanogaster; 1:200	Karim M, Endo K, Moore A, Taniguchi H. Whole mount immunolabeling of olfactory receptor neurons in the Drosophila antenna. J Vis Exp. 2014;: pubmed publisher
	Ramaekers A, Claeys A, Kapun M, Mouchel Vielh E, Potier D, Weinberger S, et al. Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs. Dev Cell. 2019;50:780-792.e7 pubmed publisher
	Ojelade S, Lee T, Giagtzoglou N, Yu L, Ugur B, Li Y, et al. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019;28:1799-1813.e5 pubmed publisher
	Thuveson M, Gaengel K, Collu G, Chin M, Singh J, Mlodzik M. Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix. Open Biol. 2019;9:190148 pubmed publisher
	Kanca O, Andrews J, Lee P, Patel C, Braddock S, Slavotinek A, et al. De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. Am J Hum Genet. 2019;105:413-424 pubmed publisher
	Politano S, Salemme R, Ashley J, López Rivera J, Bakula T, Puhalla K, et al. Tao Negatively Regulates BMP Signaling During Neuromuscular Junction Development in Drosophila. Dev Neurobiol. 2019;79:335-349 pubmed publisher
	Zhu J, Ordway A, Weber L, Buddika K, Kumar J. Polycomb group (PcG) proteins and Pax6 cooperate to inhibit in vivo reprogramming of the developing Drosophila eye. Development. 2018;145: pubmed publisher
	Toegel M, Azzam G, Lee E, Knapp D, Tan Y, Fa M, et al. A multiplexable TALE-based binary expression system for in vivo cellular interaction studies. Nat Commun. 2017;8:1663 pubmed publisher
	Zhou Q, Yu L, Friedrich M, Pignoni F. Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye. Dev Biol. 2017;421:67-76 pubmed publisher
	Bras Pereira C, Potier D, Jacobs J, Aerts S, Casares F, Janody F. dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis. PLoS Genet. 2016;12:e1006204 pubmed publisher
	Li T, Fan J, Blanco Sanchez B, Giagtzoglou N, Lin G, Yamamoto S, et al. Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. PLoS Genet. 2016;12:e1006054 pubmed publisher
	Liang X, Mahato S, Hemmerich C, Zelhof A. Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation. Dev Biol. 2016;414:4-20 pubmed publisher
	Corty M, Tam J, Grueber W. Dendritic diversification through transcription factor-mediated suppression of alternative morphologies. Development. 2016;143:1351-62 pubmed publisher
	Fu W, Sun J, Huang G, Liu J, Kaufman A, Ryan R, et al. Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation. J Biol Chem. 2016;291:6200-17 pubmed publisher
	Matsuo E, Seki H, Asai T, Morimoto T, Miyakawa H, Ito K, et al. Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster. J Comp Neurol. 2016;524:1099-164 pubmed publisher
	Grillo Hill B, Choi C, Jimenez Vidal M, Barber D. Increased Hâº efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression. elife. 2015;4: pubmed publisher
	Laneve P, Delaporte C, Trebuchet G, Komonyi O, Flici H, Popkova A, et al. The Gcm/Glide molecular and cellular pathway: new actors and new lineages. Dev Biol. 2013;375:65-78 pubmed publisher
	Hara Y, Hirai K, Togane Y, Akagawa H, Iwabuchi K, Tsujimura H. Ecdysone-dependent and ecdysone-independent programmed cell death in the developing optic lobe of Drosophila. Dev Biol. 2013;374:127-41 pubmed publisher
	Beck E, Gasque G, Imlach W, Jiao W, Jiwon Choi B, Wu P, et al. Regulation of Fasciclin II and synaptic terminal development by the splicing factor beag. J Neurosci. 2012;32:7058-73 pubmed publisher
	Miyazaki T, Ito K. Neural architecture of the primary gustatory center of Drosophila melanogaster visualized with GAL4 and LexA enhancer-trap systems. J Comp Neurol. 2010;518:4147-81 pubmed publisher
	Potter C, Tasic B, Russler E, Liang L, Luo L. The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis. Cell. 2010;141:536-48 pubmed publisher
	Simon F, Fichelson P, Gho M, Audibert A. Notch and Prospero repress proliferation following cyclin E overexpression in the Drosophila bristle lineage. PLoS Genet. 2009;5:e1000594 pubmed publisher
	Edwards T, Meinertzhagen I. Photoreceptor neurons find new synaptic targets when misdirected by overexpressing runt in Drosophila. J Neurosci. 2009;29:828-41 pubmed publisher
	Hong S, Qi W, Brabant M, Bosco G, Martinez J. Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster. Cell Div. 2008;3:2 pubmed publisher
	Doroquez D, Orr Weaver T, Rebay I. Split ends antagonizes the Notch and potentiates the EGFR signaling pathways during Drosophila eye development. Mech Dev. 2007;124:792-806 pubmed
	Kamikouchi A, Shimada T, Ito K. Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster. J Comp Neurol. 2006;499:317-56 pubmed
	Sugimura K, Satoh D, Estes P, Crews S, Uemura T. Development of morphological diversity of dendrites in Drosophila by the BTB-zinc finger protein abrupt. Neuron. 2004;43:809-22 pubmed
	Li Y, Lei L, Irvine K, Baker N, Li L. Notch activity in neural cells triggered by a mutant allele with altered glycosylation. Development. 2003;130:2829-40 pubmed
	Li Y, Fetchko M, Lai Z, Baker N. Scabrous and Gp150 are endosomal proteins that regulate Notch activity. Development. 2003;130:2819-27 pubmed
	Takamatsu Y, Kishimoto Y, Ohsako S. Immunohistochemical study of Ca2+/calmodulin-dependent protein kinase II in the Drosophila brain using a specific monoclonal antibody. Brain Res. 2003;974:99-116 pubmed
	Yang L, Baker N. Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye. Dev Cell. 2003;4:359-69 pubmed
	Okajima T, Irvine K. Regulation of notch signaling by o-linked fucose. Cell. 2002;111:893-904 pubmed
	Li Y, Baker N. Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye. Curr Biol. 2001;11:330-8 pubmed
	Baker N, Yu S. The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye. Cell. 2001;104:699-708 pubmed
	Nagel A, Maier D, Preiss A. Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila. Mech Dev. 2000;94:3-12 pubmed
	Suzuki T, Saigo K. Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus. Development. 2000;127:1531-40 pubmed
	Nagel A, Preiss A. Notchspl is deficient for inductive processes in the eye, and E(spl)D enhances split by interfering with proneural activity. Dev Biol. 1999;208:406-15 pubmed
	O Neill E, Rebay I, Tjian R, Rubin G. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell. 1994;78:137-47 pubmed

product information

Internal ID :

1915

Name :

Rat-Elav-7E8A10 anti-elav

Depositor Name :

Rubin, G.M.

Depositor Institution :

HHMI / Janelia Farm Research

Date Deposited :

8/31/94

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

elav Drosophila protein; embryonic lethal abnormal vision

Antigen Species :

Drosophila

Host Species :

rat

Isotype :

RIgG2a

Isotype for catalog (legacy) :

IgG2a

Positive Tested Species Reactivity :

Drosophila

Initial Publication Pubmed ID :

8033205

Depositor Notes (Special Instructions) :

This antibody is a marker for most differentiated neuronal cells in the central and peripheral nervous system.

Collections :

Drosophila antigens,Neurodevelopment

Search Keywords :

Rubin, Gerald M., elav Drosophila protein; embryonic lethal abnormal vision, Drosophila, RIgG2a, Drosophila, elav, elav-2, elav-3, fliJ, weg, AB_528218, monoclonal

Antigen Molecular Weight :

50.8 kD Predicted

Gene :

elav

Alternate Gene Name(s) :

elav-2, elav-3, fliJ, weg

Uniprot ID :

P16914

Antibody Registry ID :

AB_528218

Immunogen :

Recombinant protein

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry

Immunohistochemistry Pubmed IDs :

23149076 23276603 22593074 20434990 19662164 18194556 19158307 17588724 15363392 12756167 12756168 12742628 12636917 12526814 11257224 11267869 10842054 10842054 10191054 16998934 20878781 10704398 25793441 27095495 29162808 31412248 31409231 31447264

Immunofluorescence Pubmed IDs :

17588724 27195754 27442438 27693434 26762251 29530880 27105580 27151460 26792857 31002474 31327508 31318331

DSHB Growth Medium :

Iscove's

References (legacy) :

Cell 78, 137-147.; Dev. Biol. 208, 406-415.; Mech. Dev. 94, 3-12.; Development 128, 1183-1191.; Curr. Biol. 11, 330-338.; Cell 104, 699-708.; Cell 111, 893-904.; Development 130, 2819-2827.; Development 130, 2829-2840.; Dev. Cell 4, 359-369.; Brain Res. 974, 99-116.; Neuron 43, 809-822.; J. Neurosci. 29(3), 828-841.; Cell 141(3), 536-548.; J. Neurosci. 32(20), 7058-7073.; Dev. Biol. 375, 65-78.

more info or order :

Developmental Studies Hybridoma Bank product webpage