product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Nestin (intermediate filament protein)
catalog :
Rat-401
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
rat-401
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 95
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3c
Chleilat E, Pethe A, Pfeifer D, Krieglstein K, Roussa E. TGF-β Signaling Regulates SLC8A3 Expression and Prevents Oxidative Stress in Developing Midbrain Dopaminergic and Dorsal Raphe Serotonergic Neurons. Int J Mol Sci. 2020;21: pubmed publisher
  • immunocytochemistry; mouse; 1:4; loading ...; fig 1d
Montalbán Loro R, Lozano Ureña A, Ito M, Krueger C, Reik W, Ferguson Smith A, et al. TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn. Nat Commun. 2019;10:1726 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 1h
Lü Y, Dong E, Yang W, Lai L, Lin X, Ma L, et al. Generation of an integration-free induced pluripotent stem cell line, FJMUi001-A, from a hereditary spastic paraplegia patient carrying compound heterozygous p.P498L and p.R618W mutations in CAPN1 (SPG76). Stem Cell Res. 2019;34:101354 pubmed publisher
  • immunocytochemistry; mouse; 1:5; loading ...; fig 1a
Paul A, Chaker Z, Doetsch F. Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis. Science. 2017;356:1383-1386 pubmed publisher
  • immunohistochemistry; mouse; 1:40; fig 8a
Subashini C, Dhanesh S, Chen C, Riya P, Meera V, Divya T, et al. Wnt5a is a crucial regulator of neurogenesis during cerebellum development. Sci Rep. 2017;7:42523 pubmed publisher
  • immunocytochemistry; mouse; 1:10; fig s10d
Bressan R, Dewari P, Kalantzaki M, Gangoso E, Matjusaitis M, Garcia Diaz C, et al. Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells. Development. 2017;144:635-648 pubmed publisher
  • immunocytochemistry; mouse; fig 5s1
Deaton A, Gómez Rodríguez M, Mieczkowski J, Tolstorukov M, Kundu S, Sadreyev R, et al. Enhancer regions show high histone H3.3 turnover that changes during differentiation. elife. 2016;5: pubmed publisher
  • immunocytochemistry; rat; 1:4; fig 2a
Del Debbio C, Mir Q, Parameswaran S, Mathews S, Xia X, Zheng L, et al. Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1. PLoS ONE. 2016;11:e0152025 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 2
Dooves S, Bugiani M, Postma N, Polder E, Land N, Horan S, et al. Astrocytes are central in the pathomechanisms of vanishing white matter. J Clin Invest. 2016;126:1512-24 pubmed publisher
  • immunocytochemistry; mouse; 1:300; fig 2
  • immunohistochemistry; mouse; 1:300; fig s2
Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, et al. LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 4a
Kovacs G, Szabo V, Pirity M. Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells. Stem Cells Int. 2016;2016:4034620 pubmed publisher
  • immunohistochemistry; mouse; 1:150; fig 4
Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, et al. Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015;8:53 pubmed publisher
  • immunohistochemistry; mouse; 1:20; fig s4
Maza I, Caspi I, Zviran A, Chomsky E, Rais Y, Viukov S, et al. Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors. Nat Biotechnol. 2015;33:769-74 pubmed publisher
  • immunohistochemistry; mouse; tbl 2
Andrews W, Davidson K, Tamamaki N, Ruhrberg C, Parnavelas J. Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice. J Comp Neurol. 2016;524:518-34 pubmed publisher
  • immunocytochemistry; human; fig 1
Buonora J, Mousseau M, Jacobowitz D, Lazarus R, Yarnell A, Olsen C, et al. Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker. J Neurotrauma. 2015;32:1805-14 pubmed publisher
  • immunocytochemistry; human; fig 4
Crouch E, Liu C, Silva Vargas V, Doetsch F. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015;35:4528-39 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig s8c
Paez Gonzalez P, Asrican B, Rodriguez E, Kuo C. Identification of distinct ChAT? neurons and activity-dependent control of postnatal SVZ neurogenesis. Nat Neurosci. 2014;17:934-42 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Akeju O, Davis Dusenbery B, Cassel S, Ichida J, Eggan K. Ketamine exposure in early development impairs specification of the primary germ cell layers. Neurotoxicol Teratol. 2014;43:59-68 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:4
Gallaher Z, Johnston S, Czaja K. Neural proliferation in the dorsal root ganglia of the adult rat following capsaicin-induced neuronal death. J Comp Neurol. 2014;522:3295-307 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Nguyen H, Ostendorf A, Satz J, Westra S, Ross Barta S, Campbell K, et al. Glial scaffold required for cerebellar granule cell migration is dependent on dystroglycan function as a receptor for basement membrane proteins. Acta Neuropathol Commun. 2013;1:58 pubmed publisher
  • immunocytochemistry; dogs
Tobias I, Brooks C, Teichroeb J, Betts D. Derivation and culture of canine embryonic stem cells. Methods Mol Biol. 2013;1074:69-83 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:30
  • immunocytochemistry; mouse
Brunne B, FRANCO S, Bouché E, Herz J, Howell B, Pahle J, et al. Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia. 2013;61:1347-63 pubmed publisher
  • immunocytochemistry; mouse
Liu N, Wang M, Deng W, Schmidt C, Qin W, Leonhardt H, et al. Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules. PLoS ONE. 2013;8:e62755 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Xu J, Nonogaki M, Madhira R, Ma H, Hermanson O, Kioussi C, et al. Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons. PLoS ONE. 2012;7:e48573 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Petkau T, Neal S, Orban P, MacDonald J, Hill A, Lu G, et al. Progranulin expression in the developing and adult murine brain. J Comp Neurol. 2010;518:3931-47 pubmed publisher
  • immunohistochemistry; rat; 1:20
Furmanski O, Gajavelli S, Lee J, Collado M, Jergova S, Sagen J. Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis. J Comp Neurol. 2009;515:56-71 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:250
Sakakibara S, Nakadate K, Tanaka Nakadate S, Yoshida K, Nogami S, Shirataki H, et al. Developmental and spatial expression pattern of alpha-taxilin in the rat central nervous system. J Comp Neurol. 2008;511:65-80 pubmed publisher
Gangoso E, Southgate B, Bradley L, Rus S, Gálvez Cancino F, McGivern N, et al. Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion. Cell. 2021;184:2454-2470.e26 pubmed publisher
Skop N, Singh S, Antikainen H, Saqcena C, Calderon F, Rothbard D, et al. Subacute Transplantation of Native and Genetically Engineered Neural Progenitors Seeded on Microsphere Scaffolds Promote Repair and Functional Recovery After Traumatic Brain Injury. ASN Neuro. 2019;11:1759091419830186 pubmed publisher
Pekowska A, Klaus B, Xiang W, Severino J, Daigle N, Klein F, et al. Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency. Cell Syst. 2018;7:482-495.e10 pubmed publisher
Liu Z, Hu Z. Aligned contiguous microfiber platform enhances neural differentiation of embryonic stem cells. Sci Rep. 2018;8:6087 pubmed publisher
Pfeiffer V, Götz R, Camarero G, Heinsen H, Blum R, Rapp U. Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF. PLoS ONE. 2018;13:e0192067 pubmed publisher
Nascimento M, Sorokin L, Coelho Sampaio T. Fractone Bulbs Derive from Ependymal Cells and Their Laminin Composition Influence the Stem Cell Niche in the Subventricular Zone. J Neurosci. 2018;38:3880-3889 pubmed publisher
Zhang J, Moradi E, Somekh M, Mather M. Label-Free, High Resolution, Multi-Modal Light Microscopy for Discrimination of Live Stem Cell Differentiation Status. Sci Rep. 2018;8:697 pubmed publisher
Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien W, et al. Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell. 2017;41:481-495.e5 pubmed publisher
Ishii S, Torii M, Son A, Rajendraprasad M, Morozov Y, Kawasawa Y, et al. Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. Nat Commun. 2017;8:15157 pubmed publisher
Haushalter C, Schuhbaur B, Dolle P, Rhinn M. Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development. Biol Open. 2017;6:148-160 pubmed publisher
Baye E, Gallazzini M, Delville M, Legendre C, Terzi F, Canaud G. The costimulatory receptor B7-1 is not induced in injured podocytes. Kidney Int. 2016;90:1037-1044 pubmed publisher
Abdullah A, Zhang H, Nie Y, Tang W, Sun T. CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex. Stem Cell Reports. 2016;7:69-79 pubmed publisher
Ferguson R, Subramanian V. PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes. PLoS ONE. 2016;11:e0159051 pubmed publisher
Villarreal A, Rosciszewski G, Murta V, Cadena V, Usach V, Dodes Traian M, et al. Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes. Front Cell Neurosci. 2016;10:139 pubmed publisher
Sawada T, Arai D, Jing X, Furushima K, Chen Q, Kawakami K, et al. Trans-Activation between EphA and FGFR Regulates Self-Renewal and Differentiation of Mouse Embryonic Neural Stem/Progenitor Cells via Differential Activation of FRS2α. PLoS ONE. 2015;10:e0128826 pubmed publisher
Blanco V, Chu Z, Vallabhapurapu S, Sulaiman M, Kendler A, Rixe O, et al. Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors. Oncotarget. 2014;5:7105-18 pubmed
Diensthuber M, Zecha V, Wagenblast J, Arnhold S, Edge A, Stover T. Spiral ganglion stem cells can be propagated and differentiated into neurons and glia. Biores Open Access. 2014;3:88-97 pubmed publisher
Tsakiridis A, Huang Y, Blin G, Skylaki S, Wymeersch F, Osorno R, et al. Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Development. 2014;141:1209-21 pubmed publisher
Zhou Y, Yang J, Watkins D, Boomer L, Matthews M, Su Y, et al. Enteric nervous system abnormalities are present in human necrotizing enterocolitis: potential neurotransplantation therapy. Stem Cell Res Ther. 2013;4:157 pubmed
Yumoto T, Nakadate K, Nakamura Y, Sugitani Y, Sugitani Yoshida R, Ueda S, et al. Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors. PLoS ONE. 2013;8:e79895 pubmed publisher
Zhang J, Neal J, Lian G, Hu J, Lu J, Sheen V. Filamin A regulates neuronal migration through brefeldin A-inhibited guanine exchange factor 2-dependent Arf1 activation. J Neurosci. 2013;33:15735-46 pubmed publisher
Chan W, Sideris A, Sutachan J, Montoya G J, Blanck T, Recio Pinto E. Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLC?. Front Mol Neurosci. 2013;6:23 pubmed publisher
Chaubey S, Wolfe J. Transplantation of CD15-enriched murine neural stem cells increases total engraftment and shifts differentiation toward the oligodendrocyte lineage. Stem Cells Transl Med. 2013;2:444-54 pubmed publisher
Sakane F, Miyamoto Y. N-cadherin regulates the proliferation and differentiation of ventral midbrain dopaminergic progenitors. Dev Neurobiol. 2013;73:518-29 pubmed publisher
Hahn M, Qiu R, Wu X, Li A, Zhang H, Wang J, et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep. 2013;3:291-300 pubmed publisher
Ogawa Y, Tanaka M, Tanabe M, Suzuki T, Togawa T, Fukushige T, et al. Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease. PLoS ONE. 2013;8:e55856 pubmed publisher
Watanabe M, Kang Y, Davies L, Meghpara S, Lau K, Chung C, et al. BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. J Neurosci. 2012;32:15934-45 pubmed publisher
McLoughlin H, Fineberg S, Ghosh L, Tecedor L, Davidson B. Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis. Neuroscience. 2012;223:285-95 pubmed publisher
Lee J, Jergova S, Furmanski O, Gajavelli S, Sagen J. Predifferentiated GABAergic neural precursor transplants for alleviation of dysesthetic central pain following excitotoxic spinal cord injury. Front Physiol. 2012;3:167 pubmed publisher
Bai L, Lennon D, Caplan A, Dechant A, Hecker J, Kranso J, et al. Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models. Nat Neurosci. 2012;15:862-70 pubmed publisher
Torres J, Prieto J, Durupt F, Broad S, Watt F. Efficient differentiation of embryonic stem cells into mesodermal precursors by BMP, retinoic acid and Notch signalling. PLoS ONE. 2012;7:e36405 pubmed publisher
Gaete M, Mu oz R, S nchez N, Tampe R, Moreno M, Contreras E, et al. Spinal cord regeneration in Xenopus tadpoles proceeds through activation of Sox2-positive cells. Neural Dev. 2012;7:13 pubmed publisher
Ritch J, Valencia A, Alexander J, Sapp E, Gatune L, Sangrey G, et al. Multiple phenotypes in Huntington disease mouse neural stem cells. Mol Cell Neurosci. 2012;50:70-81 pubmed publisher
Addae C, Yi X, Gernapudi R, Cheng H, Musto A, Martinez Ceballos E. All-trans-retinoid acid induces the differentiation of encapsulated mouse embryonic stem cells into GABAergic neurons. Differentiation. 2012;83:233-41 pubmed publisher
Paschaki M, Lin S, Wong R, Finnell R, Dolle P, Niederreither K. Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord. PLoS ONE. 2012;7:e32447 pubmed publisher
Bultmann S, Morbitzer R, Schmidt C, Thanisch K, Spada F, Elsaesser J, et al. Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers. Nucleic Acids Res. 2012;40:5368-77 pubmed publisher
Nowakowski T, Mysiak K, Pratt T, Price D. Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. PLoS ONE. 2011;6:e23013 pubmed publisher
Modarresi F, Faghihi M, Patel N, Sahagan B, Wahlestedt C, Lopez Toledano M. Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis. 2011;2011:929042 pubmed publisher
Cao Y, Staropoli J, Biswas S, Espinola J, MacDonald M, Lee J, et al. Distinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cells. PLoS ONE. 2011;6:e17118 pubmed publisher
Otsu M, Sai T, Nakayama T, Murakami K, Inoue N. Uni-directional differentiation of mouse embryonic stem cells into neurons by the neural stem sphere method. Neurosci Res. 2011;69:314-21 pubmed publisher
Chowdhury F, Li Y, Poh Y, Yokohama Tamaki T, Wang N, Tanaka T. Soft substrates promote homogeneous self-renewal of embryonic stem cells via downregulating cell-matrix tractions. PLoS ONE. 2010;5:e15655 pubmed publisher
Meek S, Buehr M, Sutherland L, Thomson A, Mullins J, Smith A, et al. Efficient gene targeting by homologous recombination in rat embryonic stem cells. PLoS ONE. 2010;5:e14225 pubmed publisher
Urbán N, Martín Ibáñez R, Herranz C, Esgleas M, Crespo E, Pardo M, et al. Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling. Neural Dev. 2010;5:21 pubmed publisher
Abaskharoun M, Bellemare M, Lau E, Margolis R. Glypican-1, phosphacan/receptor protein-tyrosine phosphatase-?/? and its ligand, tenascin-C, are expressed by neural stem cells and neural cells derived from embryonic stem cells. ASN Neuro. 2010;2:e00039 pubmed publisher
Suzuki S, Namiki J, Shibata S, Mastuzaki Y, Okano H. The neural stem/progenitor cell marker nestin is expressed in proliferative endothelial cells, but not in mature vasculature. J Histochem Cytochem. 2010;58:721-30 pubmed publisher
Yoshida A, Yamaguchi Y, Nonomura K, Kawakami K, Takahashi Y, Miura M. Simultaneous expression of different transgenes in neurons and glia by combining in utero electroporation with the Tol2 transposon-mediated gene transfer system. Genes Cells. 2010;15:501-12 pubmed publisher
Ramasamy S, Lenka N. Notch exhibits ligand bias and maneuvers stage-specific steering of neural differentiation in embryonic stem cells. Mol Cell Biol. 2010;30:1946-57 pubmed publisher
Marchetti G, Escuin S, van der Flier A, De Arcangelis A, Hynes R, Georges Labouesse E. Integrin alpha5beta1 is necessary for regulation of radial migration of cortical neurons during mouse brain development. Eur J Neurosci. 2010;31:399-409 pubmed publisher
Castelo Branco G, Andersson E, Minina E, Sousa K, Ribeiro D, Kokubu C, et al. Delayed dopaminergic neuron differentiation in Lrp6 mutant mice. Dev Dyn. 2010;239:211-21 pubmed publisher
Luo L, Gassman K, Petell L, Wilson C, Bewersdorf J, Shopland L. The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment. J Cell Sci. 2009;122:3729-37 pubmed publisher
North H, Zhao X, Kolk S, Clifford M, Ziskind D, Donoghue M. Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling. Development. 2009;136:2467-76 pubmed publisher
Brandl C, Florian C, Driemel O, Weber B, Morsczeck C. Identification of neural crest-derived stem cell-like cells from the corneal limbus of juvenile mice. Exp Eye Res. 2009;89:209-17 pubmed publisher
Shaked M, Weissmüller K, Svoboda H, Hortschansky P, Nishino N, Wolfl S, et al. Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS ONE. 2008;3:e2668 pubmed publisher
Qiu R, Wang X, Davy A, Wu C, Murai K, Zhang H, et al. Regulation of neural progenitor cell state by ephrin-B. J Cell Biol. 2008;181:973-83 pubmed publisher
Manzke T, Preusse S, Hülsmann S, Richter D. Developmental changes of serotonin 4(a) receptor expression in the rat pre-Bötzinger complex. J Comp Neurol. 2008;506:775-90 pubmed
Junquera C, Martínez Ciriano C, Castiella T, Serrano P, Azanza M, Junquera S. Immunohistochemical and ultrastructural characteristics of interstitial cells of Cajal in the rabbit duodenum. Presence of a single cilium. J Cell Mol Med. 2007;11:776-87 pubmed
Pirity M, Wang W, Wolf L, Tamm E, Schreiber Agus N, Cvekl A. Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol. 2007;7:39 pubmed
Girós A, Morante J, Gil Sanz C, Fairen A, Costell M. Perlecan controls neurogenesis in the developing telencephalon. BMC Dev Biol. 2007;7:29 pubmed
Patschan D, Michurina T, Shi H, Dolff S, Brodsky S, Vasilieva T, et al. Normal distribution and medullary-to-cortical shift of Nestin-expressing cells in acute renal ischemia. Kidney Int. 2007;71:744-54 pubmed
Gossrau G, Thiele J, Konang R, Schmandt T, Brüstle O. Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells. Stem Cells. 2007;25:939-49 pubmed
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed
Chen H, Tung Y, Li B, Iqbal K, Grundke Iqbal I. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging. 2007;28:1148-62 pubmed
Garelli A, Rotstein N, Politi L. Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression. Invest Ophthalmol Vis Sci. 2006;47:3017-27 pubmed
Tomita Y, Matsumura K, Wakamatsu Y, Matsuzaki Y, Shibuya I, Kawaguchi H, et al. Cardiac neural crest cells contribute to the dormant multipotent stem cell in the mammalian heart. J Cell Biol. 2005;170:1135-46 pubmed
Nakano I, Paucar A, Bajpai R, Dougherty J, Zewail A, Kelly T, et al. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. J Cell Biol. 2005;170:413-27 pubmed
Talbott J, Loy D, Liu Y, Qiu M, Bunge M, Rao M, et al. Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol. 2005;192:11-24 pubmed
Aoki M, Yamashita T, Tohyama M. EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway. J Biol Chem. 2004;279:32643-50 pubmed
Hockfield S, McKay R. Identification of major cell classes in the developing mammalian nervous system. J Neurosci. 1985;5:3310-28 pubmed
product information
Internal ID :
4136
Name :
rat-401
Depositor Name :
Hockfield, S.
Depositor Institution :
Yale University School of Medicine
Date Deposited :
1/15/93
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
Nestin (intermediate filament protein)
Antigen Species :
Rat
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Avian,Feline,Human,Mouse,Primate,Rat
Species Tested (legacy) :
recognizes rat and mouse; does not recognize cat, monkey, human
Initial Publication Pubmed ID :
4078630
Depositor Notes (Special Instructions) :
Nestin is expressed by progenitor glial cells in the CNS, Schwann cells in the PNS and early myoblast/myotubes.
Collections :
Cytoskeleton,Human,Neurodevelopment,Stem cell
Search Keywords :
Hockfield, Susan, Nestin (intermediate filament protein), Rat, MIgG1, Mouse/Human/Rat/Feline/Primate/Avian, Nes, , AB_2235915, Monoclonal
Antigen Molecular Weight :
208.7 kDa
Gene :
Nes
Uniprot ID :
P21263
Antibody Registry ID :
AB_2235915
Immunogen :
Spinal cord homogenate
Clonality :
Monoclonal
Myeloma Strain :
NS-1
Epitope Mapped :
No
Recommended Applications :
FACS,Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
24423414 24089482 23420609 23403289 22898830 21826226 20384787 19795519 21151976 19542359 25975775
Immunofluorescence Pubmed IDs :
23681951 22387464 22466603 22508027 22558462 21192990 20421592 19773359 19328783 17218404 25788671 29335508 29666444 30414923
Western Blot Pubmed IDs :
21785702 17290297 15145949
ELISA Pubmed IDs :
21785702
FACS Pubmed IDs :
22558462 20154142 30414923
DSHB Growth Medium :
RPMI
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US